Macroautophagy inhibition maintains fragmented mitochondria to foster T cell receptor-dependent apoptosis.

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第一作者： Mauro,Corrado

第一单位： Dulbecco-Telethon Institute, Venetian Institute of Molecular Medicine, Padova, Italy IRCCS Fondazione Santa Lucia, Rome, Italy.

作者： Mauro,Corrado ^[1] ; Francesca R,Mariotti ^[2] ; Laura,Trapani ^[2] ; Lucia,Taraborrelli ^[3] ; Francesca,Nazio ^[4] ; Valentina,Cianfanelli ^[5] ; Maria Eugenia,Soriano ^[6] ; Emilie,Schrepfer ^[7] ; Francesco,Cecconi ^[8] ; Luca,Scorrano ^[7] ; Silvia,Campello ^[9]

作者单位： Dulbecco-Telethon Institute, Venetian Institute of Molecular Medicine, Padova, Italy IRCCS Fondazione Santa Lucia, Rome, Italy. ^[1] IRCCS Fondazione Santa Lucia, Rome, Italy. ^[2] Centre for Cell Death, Cancer, and Inflammation (CCCI), UCL Cancer Institute, University College London, London, UK. ^[3] Department of Pediatric Hematology and Oncology, IRCCS Bambino Gesù Children's Hospital, Rome, Italy Department of Biology, University of Rome Tor Vergata, Rome, Italy. ^[4] Unit of Cell Stress and Survival, Danish Cancer Society Research Center, Copenhagen, Denmark. ^[5] Department of Biology, University of Padova, Padova, Italy. ^[6] Dulbecco-Telethon Institute, Venetian Institute of Molecular Medicine, Padova, Italy Department of Biology, University of Padova, Padova, Italy. ^[7] IRCCS Fondazione Santa Lucia, Rome, Italy Department of Biology, University of Rome Tor Vergata, Rome, Italy Unit of Cell Stress and Survival, Danish Cancer Society Research Center, Copenhagen, Denmark. ^[8] IRCCS Fondazione Santa Lucia, Rome, Italy Department of Biology, University of Rome Tor Vergata, Rome, Italy silvia.campello@uniroma2.it. ^[9]

关键词 AICD T cells autophagy mitochondrial dynamics