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Determination of (2)H-enrichment of rat brain interstitial fluid and rat plasma by headspace-gas-chromatography - quadrupole-mass-spectrometry.

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第一作者： Anita,Eberl

第一单位： Health - Institute for Biomedicine and Health Sciences, Joanneum Research Forschungsgesellschaft m.b.H, Neue Stiftingtalstrasse 2, 8010, Graz, Austria.

作者： Anita,Eberl ^[1] ; Thomas,Altendorfer-Kroath ^[1] ; Denise,Kollmann ^[2] ; Thomas,Birngruber ^[1] ; Frank,Sinner ^[3] ; Reingard,Raml ^[4] ; Christoph,Magnes ^[1]

作者单位： Health - Institute for Biomedicine and Health Sciences, Joanneum Research Forschungsgesellschaft m.b.H, Neue Stiftingtalstrasse 2, 8010, Graz, Austria. ^[1] Division of Endocrinology and Diabetology, Department of Internal Medicine, Medical University of Graz, Auenbruggerplatz 15, 8036, Graz, Austria. ^[2] Health - Institute for Biomedicine and Health Sciences, Joanneum Research Forschungsgesellschaft m.b.H, Neue Stiftingtalstrasse 2, 8010, Graz, Austria; Division of Endocrinology and Diabetology, Department of Internal Medicine, Medical University of Graz, Auenbruggerplatz 15, 8036, Graz, Austria. ^[3] Health - Institute for Biomedicine and Health Sciences, Joanneum Research Forschungsgesellschaft m.b.H, Neue Stiftingtalstrasse 2, 8010, Graz, Austria. Electronic address: reingard.raml@joanneum.at. ^[4]

关键词 (2)H(2)O Cerebral open flow microperfusion Headspace GC-MS Interstitial fluid Plasma Validation

医学主题词动物(Animals);脑(Brain);氘交换测定(Deuterium Exchange Measurement);氧化氘(Deuterium Oxide);细胞外液(Extracellular Fluid);气相色谱-质谱法(Gas Chromatography-Mass Spectrometry);大鼠(Rats)

DOI 10.1016/j.ab.2016.07.010

PMID 27402176

发布时间 2018-02-07

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