Germline MC1R status influences somatic mutation burden in melanoma.-论文-万方医学网

作者： Carla Daniela,Robles-Espinoza ^[1] ; Nicola D,Roberts ^[2] ; Shuyang,Chen ^[1] ; Finbarr P,Leacy ^[3] ; Ludmil B,Alexandrov ^[4] ; Natapol,Pornputtapong ^[5] ; Ruth,Halaban ^[6] ; Michael,Krauthammer ^[3] ; Rutao,Cui ^[7] ; D,Timothy Bishop ^[8] ; David J,Adams ^[7]

作者单位： Experimental Cancer Genetics, The Wellcome Trust Sanger Institute, Hinxton, Cambridgeshire CB10 1SA, UK. ^[1] Laboratorio Internacional de Investigación sobre el Genoma Humano, Universidad Nacional Autónoma de México, Campus Juriquilla, Boulevard Juriquilla 3001, Santiago de Querétaro 76230, Mexico. ^[2] The Cancer Genome Project, The Wellcome Trust Sanger Institute, Hinxton, Cambridgeshire CB10 1SA, UK. ^[3] Department of Pharmacology and Experimental Therapeutics, Boston University School of Medicine. Boston, Massachusetts 02118, USA. ^[4] MRC Biostatistics Unit, Cambridge Institute of Public Health, Cambridge Biomedical Campus, Cambridge CB2 0SR, UK. ^[5] Division of Population Health Sciences, Royal College of Surgeons in Ireland, Lower Mercer Street, Dublin 2, Ireland. ^[6] Department of Pathology, Yale University School of Medicine, New Haven, Connecticut 06519, USA. ^[7] Department of Dermatology, Yale University School of Medicine, New Haven, Connecticut 06519, USA. ^[8] Program in Computational Biology and Bioinformatics, Yale University School of Medicine, New Haven, Connecticut 06519, USA. ^[9] Section of Epidemiology and Biostatistics, Leeds Institute of Cancer and Pathology, University of Leeds, Leeds, LS9 7TF, UK. ^[10]

主题词老年人(Aged);等位基因(Alleles);队列研究(Cohort Studies);女(雌)性(Female);疾病遗传易感性(Genetic Predisposition to Disease);遗传变异(Genetic Variation);生殖细胞系突变(Germ-Line Mutation);毛发颜色(Hair Color);头颈部肿瘤(Head and Neck Neoplasms);人类(Humans);男(雄)性(Male);黑色素瘤(Melanoma);黑变病(Melanosis);中年人(Middle Aged);突变(Mutation);肿瘤侵润(Neoplasm Invasiveness);多态性, 单核苷酸(Polymorphism, Single Nucleotide);受体, 黑皮质素, 1型(Receptor, Melanocortin, Type 1);皮肤肿瘤(Skin Neoplasms);皮肤色素沉着(Skin Pigmentation)

DOI 10.1038/ncomms12064

PMID 27403562

发布时间 2024-02-10

检索历史清除

Germline MC1R status influences somatic mutation burden in melanoma.

Nature communications

相似文献

Nature communications

相关期刊

参考文献：
指定格式：	NoteExpress EndNote RefWorks NoteFirst

检索历史 清除

Germline MC1R status influences somatic mutation burden in melanoma.

Nature communications

相似文献

Nature communications

相关期刊

检索历史清除