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Lipid-based oral delivery systems for skin deposition of a potential chemopreventive DIM derivative: characterization and evaluation.

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第一作者： Cedar H A,Boakye

第一单位： College of Pharmacy and Pharmaceutical Sciences, Florida A&M University, 1520 S Martin Luther King Jr. Blvd, Tallahassee, FL, 32307, USA.

作者： Cedar H A,Boakye ^[1] ; Ketan,Patel ^[1] ; Apurva R,Patel ^[1] ; Henrique A M,Faria ^[2] ; Valtencir,Zucolotto ^[2] ; Stephen,Safe ^[3] ; Mandip,Singh ^[4]

作者单位： College of Pharmacy and Pharmaceutical Sciences, Florida A&M University, 1520 S Martin Luther King Jr. Blvd, Tallahassee, FL, 32307, USA. ^[1] Nanomedicine and Nanotoxicology Group, Physics Institute of São Carlos, USP, São Carlos, SP, 13566-590, Brazil. ^[2] Department of Veterinary Physiology and Pharmacology, Texas A&M University, College Station, TX, USA. ^[3] College of Pharmacy and Pharmaceutical Sciences, Florida A&M University, 1520 S Martin Luther King Jr. Blvd, Tallahassee, FL, 32307, USA. mandip.sachdeva@gmail.com. ^[4]

关键词 Diindolylmethane (DIM)First pass metabolism Lipid-based drug delivery systems Oral delivery P-glycoprotein efflux pump Skin delivery