The miR-644a/CTBP1/p53 axis suppresses drug resistance by simultaneous inhibition of cell survival and epithelial-mesenchymal transition in breast cancer.-论文-万方医学网

作者： Umar,Raza ^[1] ; Özge,Saatci ^[1] ; Stefan,Uhlmann ^[2] ; Suhail A,Ansari ^[1] ; Erol,Eyüpoğlu ^[1] ; Emre,Yurdusev ^[1] ; Merve,Mutlu ^[1] ; Pelin Gülizar,Ersan ^[1] ; Mustafa Kadri,Altundağ ^[3] ; Jitao David,Zhang ^[4] ; Hayriye Tatlı,Doğan ^[5] ; Gülnur,Güler ^[5] ; Özgür,Şahin ^[1]

作者单位： Department of Molecular Biology and Genetics, Faculty of Science, Bilkent University, 06800 Ankara, Turkey. ^[1] Friedrich Miescher Institute for Biomedical Research, Maulbeerstrasse 66, 4058 Basel, Switzerland. ^[2] Department of Medical Oncology, Hacettepe University Cancer Institute, 06410 Ankara, Turkey. ^[3] Bäumlihofstrasse 429, 4125 Riehen, Switzerland. ^[4] Department of Pathology, Hacettepe University, 06410 Ankara, Turkey. ^[5]

主题词醇氧化还原酶类(Alcohol Oxidoreductases);动物(Animals);细胞凋亡(Apoptosis);乳腺肿瘤(Breast Neoplasms);细胞周期(Cell Cycle);细胞系, 肿瘤(Cell Line, Tumor);细胞运动(Cell Movement);细胞存活(Cell Survival);DNA结合蛋白质类(DNA-Binding Proteins);疾病恶化(Disease Progression);抗药性, 肿瘤(Drug Resistance, Neoplasm);上皮-间质转化(Epithelial-Mesenchymal Transition);女(雌)性(Female);基因表达调控, 肿瘤(Gene Expression Regulation, Neoplastic);人类(Humans);小鼠(Mice);小鼠, 裸(Mice, Nude);微RNAs(MicroRNAs);突变(Mutation);肿瘤转移(Neoplasm Metastasis);肿瘤复发, 局部(Neoplasm Recurrence, Local);肿瘤移植(Neoplasm Transplantation);肿瘤抑制蛋白质p53(Tumor Suppressor Protein p53)

DOI 10.18632/oncotarget.10489

PMID 27409664

发布时间 2018-11-13

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The miR-644a/CTBP1/p53 axis suppresses drug resistance by simultaneous inhibition of cell survival and epithelial-mesenchymal transition in breast cancer.

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The miR-644a/CTBP1/p53 axis suppresses drug resistance by simultaneous inhibition of cell survival and epithelial-mesenchymal transition in breast cancer.

Oncotarget

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Oncotarget

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