High-efficiency transduction and specific expression of ChR2opt for optogenetic manipulation of primary cortical neurons mediated by recombinant adeno-associated viruses.

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作者： Lei,Jin ^[1] ; Wienke,Lange ^[2] ; Annika,Kempmann ^[3] ; Vanessa,Maybeck ^[4] ; Anne,Günther ^[5] ; Nadine,Gruteser ^[6] ; Arnd,Baumann ^[7] ; Andreas,Offenhäusser ^[8]

作者单位： Institute of Complex Systems ICS-8, Forschungszentrum Jülich, Leo-Brandt-Str., 52428 Jülich, Germany. Electronic address: lei.jin@fz-juelich.de. ^[1] Institute of Complex Systems ICS-8, Forschungszentrum Jülich, Leo-Brandt-Str., 52428 Jülich, Germany. Electronic address: wienke.lange@web.de. ^[2] Institute of Complex Systems ICS-4, Forschungszentrum Jülich, Leo-Brandt-Str., 52428 Jülich, Germany. Electronic address: Annika.meisenberg@gmail.com. ^[3] Institute of Complex Systems ICS-8, Forschungszentrum Jülich, Leo-Brandt-Str., 52428 Jülich, Germany. Electronic address: v.maybeck@fz-juelich.de. ^[4] Institute of Complex Systems ICS-4, Forschungszentrum Jülich, Leo-Brandt-Str., 52428 Jülich, Germany. Electronic address: guenther_a@gmx.net. ^[5] Institute of Complex Systems ICS-4, Forschungszentrum Jülich, Leo-Brandt-Str., 52428 Jülich, Germany. Electronic address: nadine.gruteser@t-online.de. ^[6] Institute of Complex Systems ICS-4, Forschungszentrum Jülich, Leo-Brandt-Str., 52428 Jülich, Germany. Electronic address: a.baumann@fz-juelich.de. ^[7] Institute of Complex Systems ICS-8, Forschungszentrum Jülich, Leo-Brandt-Str., 52428 Jülich, Germany. Electronic address: a.offenhaeusser@fz-juelich.de. ^[8]

关键词 Channelrhodopsin Electrophysiology Neuronal networks