Transcriptional and epigenetic mechanisms of cellular reprogramming to induced pluripotency.

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作者： Mark,van den Hurk ^[1] ; Gunter,Kenis ^[2] ; Cedric,Bardy ^[3] ; Daniel L,van den Hove ^[1] ; Fred H,Gage ^[2] ; Harry W,Steinbusch ^[3] ; Bart P,Rutten ^[1]

作者单位： Department of Psychiatry & Neuropsychology, Division of Translational Neuroscience, Maastricht University, Maastricht, 6200 MD, The Netherlands. ^[1] European Graduate School of Neuroscience (EURON), Maastricht University, Maastricht, 6200 MD, The Netherlands. ^[2] Laboratory of Genetics, The Salk Institute for Biological Studies, La Jolla, CA 92037, USA. ^[3] Laboratory of Translational Neuroscience, Department of Psychiatry, Psychosomatics & Psychotherapy, University of Wuerzburg, 97080 Wuerzburg, Germany. ^[4]

关键词 DNA methylation chromatin epigenetics histone modifications iPSC induced pluripotent stem cell pluripotency reprogramming

主题词动物(Animals);染色质组装和分解(Chromatin Assembly and Disassembly);DNA甲基化(DNA Methylation);后成说, 遗传(Epigenesis, Genetic);人类(Humans);诱导多能干细胞(Induced Pluripotent Stem Cells);转录, 遗传(Transcription, Genetic)

DOI 10.2217/epi-2016-0032

PMID 27419933

发布时间 2021-12-04

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