Structural Plasticity of Cholesteryl Ester Transfer Protein Assists the Lipid Transfer Activity.

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第一作者： Venkat R,Chirasani

第一单位： From the Bhupat and Jyoti Mehta School of Biosciences and Department of Biotechnology, Indian Institute of Technology Madras, Chennai 600036, India.

作者： Venkat R,Chirasani ^[1] ; Prasanna D,Revanasiddappa ^[1] ; Sanjib,Senapati ^[2]

作者单位： From the Bhupat and Jyoti Mehta School of Biosciences and Department of Biotechnology, Indian Institute of Technology Madras, Chennai 600036, India. ^[1] From the Bhupat and Jyoti Mehta School of Biosciences and Department of Biotechnology, Indian Institute of Technology Madras, Chennai 600036, India sanjibs@iitm.ac.in. ^[2]

关键词 cholesteryl ester (CE)cholesteryl ester transfer protein (CETP)conformational change free energy lipid binding protein lipid transport lipid-protein interaction molecular dynamics molecular dynamics simulations tunnel mechanism

主题词胆固醇酯转运蛋白质类(Cholesterol Ester Transfer Proteins);胆固醇酯类(Cholesterol Esters);结晶学, X线(Crystallography, X-Ray);人类(Humans);构效关系(Structure-Activity Relationship);甘油三酯类(Triglycerides)

DOI 10.1074/jbc.M116.744623

PMID 27445332

发布时间 2021-02-05

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