MicroRNA fingerprints in juvenile myelomonocytic leukemia (JMML) identified miR-150-5p as a tumor suppressor and potential target for treatment.

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第一作者： Pier Paolo,Leoncini

第一单位： Department of Pediatric Hematology and Oncology, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Bambino Gesù Children's Hospital, Rome, Italy.

作者： Pier Paolo,Leoncini ^[1] ; Alice,Bertaina ^[2] ; Dimitrios,Papaioannou ^[1] ; Christian,Flotho ^[2] ; Riccardo,Masetti ^[3] ; Silvia,Bresolin ^[4] ; Giuseppe,Menna ^[5] ; Nicola,Santoro ^[6] ; Marco,Zecca ^[7] ; Giuseppe,Basso ^[8] ; Giovanni,Nigita ^[9] ; Dario,Veneziano ^[6] ; Sara,Pagotto ^[10] ; Katia,D'Ovidio ^[10] ; Rossella,Rota ^[11] ; Adrienne,Dorrance ^[1] ; Carlo M,Croce ^[1] ; Charlotte,Niemeyer ^[3] ; Franco,Locatelli ^[10] ; Ramiro,Garzon ^[4]

作者单位： Department of Pediatric Hematology and Oncology, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Bambino Gesù Children's Hospital, Rome, Italy. ^[1] Department of Medical, Oral and Biotechnological Sciences, G. d'Annunzio University, Chieti, Italy. ^[2] Division of Hematology, Arthur G. James Comprehensive Cancer Center, The Ohio State University, Columbus, OH, USA. ^[3] Department of Pediatrics and Adolescent Medicine, Division of Pediatric Hematology and Oncology, University of Freiburg, Freiburg, Germany. ^[4] Department of Pediatrics, "Lalla Seràgnoli" Hematology-Oncology Unit, University of Bologna, Bologna, Italy. ^[5] Department of Woman and Child Health, Haemato-Oncology Division, University of Padova, Azienda Ospedaliera di Padova, Padova, Italy. ^[6] Department of Paediatric Haemato-Oncology, Santobono-Pausilipon Hospital, Napoli, Italy. ^[7] Department of Paediatrics, Paediatric Unit 'F. Vecchio', University of Bari, Bari, Italy. ^[8] Department of Paediatric Haematology and Oncology, Fondazione IRCCS Policlinico S. Matteo, University of Pavia, Pavia, Italy. ^[9] Department of Molecular Virology, Immunology and Medical Genetics, The Ohio State University, Columbus, OH, USA. ^[10] Unit of General Pathology, Center of Excellence on Aging and Translational Medicine (CeSI-MeT), G. d'Annunzio University, Chieti, Italy. ^[11]

关键词 GM-CSF JMML STAT5b miR-150 microRNA