Cytoskeletal interference - A new mode of action for the anticancer drugs camptothecin and topotecan.

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作者： Xiaojuan,Wang ^[1] ; Mine,Tanaka ^[2] ; Sonja,Krstin ^[3] ; Herbenya Silva,Peixoto ^[4] ; Carina Carneiro de Melo,Moura ^[5] ; Michael,Wink ^[6]

作者单位： Department of Biology, Institute of Pharmacy and Molecular Biotechnology, Heidelberg University, Heidelberg, Germany. Electronic address: wxjsz@hotmail.com. ^[1] Department of Biology, Institute of Pharmacy and Molecular Biotechnology, Heidelberg University, Heidelberg, Germany. Electronic address: mine_tanaka@hotmail.com. ^[2] Department of Biology, Institute of Pharmacy and Molecular Biotechnology, Heidelberg University, Heidelberg, Germany. Electronic address: Krstin@uni-heidelberg.de. ^[3] Department of Biology, Institute of Pharmacy and Molecular Biotechnology, Heidelberg University, Heidelberg, Germany. Electronic address: hspeixoto1@gmail.com. ^[4] Department of Biology, Institute of Pharmacy and Molecular Biotechnology, Heidelberg University, Heidelberg, Germany. Electronic address: c.carneiro@stud.uni-heidelberg.de. ^[5] Department of Biology, Institute of Pharmacy and Molecular Biotechnology, Heidelberg University, Heidelberg, Germany. Electronic address: wink@uni-heidelberg.de. ^[6]

关键词 Actin filament Camptothecin Camptothecin (PubChem CID: 24360)Colchicine (PubChem CID: 6167)DNA topoisomerase Latrunculin B (PubChem CID: 6436219)Microtubule Topotecan Topotecan (PubChem CID: 60700)Vinblastine (PubChem CID: 13342)