Interaction between synaptic inhibition and glial-potassium dynamics leads to diverse seizure transition modes in biophysical models of human focal seizures.

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作者： E C,Y Ho ^[1] ; Wilson,Truccolo ^[2]

作者单位： Department of Neuroscience & Institute for Brain Science, Brown University, Providence, RI, USA. ernest_ho@brown.edu. ^[1] U.S. Department of Veterans Affairs, Center for Neurorestoration and Neurotechnology, Providence, RI, USA. ernest_ho@brown.edu. ^[2] Department of Neuroscience & Institute for Brain Science, Brown University, Providence, RI, USA. wilson_truccolo@brown.edu. ^[3] U.S. Department of Veterans Affairs, Center for Neurorestoration and Neurotechnology, Providence, RI, USA. wilson_truccolo@brown.edu. ^[4]

关键词 Focal epilepsy Gamma oscillations Seizure dynamics Spike-wave discharges

主题词人类(Humans);模型, 神经学(Models, Neurological);新皮质(Neocortex);神经胶质(Neuroglia);钾(Potassium);发作(Seizures)

DOI 10.1007/s10827-016-0615-7

PMID 27488433

发布时间 2024-03-30

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