换一批The absence of p53 during Human Cytomegalovirus infection leads to decreased UL53 expression, disrupting UL50 localization to the inner nuclear membrane, and thereby inhibiting capsid nuclear egress.
第一作者：
Man I,Kuan
第一单位：
Department of Biological Sciences and Center for Reproductive Biology, University of Idaho, Moscow, ID, USA.
作者：
医学主题词
衣壳蛋白质类(Capsid Proteins);细胞系(Cell Line);细胞核(Cell Nucleus);巨细胞病毒(Cytomegalovirus);巨细胞病毒感染(Cytomegalovirus Infections);基因表达调控, 病毒(Gene Expression Regulation, Viral);基因敲除技术(Gene Knockout Techniques);宿主与病原体相互作用(Host-Pathogen Interactions);人类(Humans);核被膜(Nuclear Envelope);蛋白质结合(Protein Binding);蛋白质转运(Protein Transport);肿瘤抑制蛋白质p53(Tumor Suppressor Protein p53);病毒蛋白质类(Viral Proteins)
DOI
10.1016/j.virol.2016.07.020
PMID
27498409
发布时间
2024-05-30
基金项目
P20 GM103408/GM/NIGMS NIH HHS/United States
P20 RR015587/RR/NCRR NIH HHS/United States
R01 AI051463/AI/NIAID NIH HHS/United States
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