Treatment with NAD(+) inhibited experimental autoimmune encephalomyelitis by activating AMPK/SIRT1 signaling pathway and modulating Th1/Th17 immune responses in mice.
作者:
主题词
AMP活化蛋白激酶类(AMP-Activated Protein Kinases);动物(Animals);脑脊髓炎, 自身免疫性, 实验性(Encephalomyelitis, Autoimmune, Experimental);女(雌)性(Female);人类(Humans);炎症(Inflammation);小鼠(Mice);小鼠, 近交C57BL(Mice, Inbred C57BL);多发性硬化(Multiple Sclerosis);NAD(NAD);信号传导(Signal Transduction);抗衰老酶1(Sirtuin 1);Th1细胞(Th1 Cells);Th17细胞(Th17 Cells)
DOI
10.1016/j.intimp.2016.07.036
PMID
27500459
发布时间
2017-11-16
- 浏览4
International immunopharmacology
287-294页
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