Nanoroughened adhesion-based capture of circulating tumor cells with heterogeneous expression and metastatic characteristics.

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第一作者： Weiqiang,Chen

第一单位： Department of Mechanical Engineering, University of Michigan, Ann Arbor, MI, 48109, USA.;Department of Mechanical and Aerospace Engineering, New York University, New York, NY, 10012, USA.

作者： Weiqiang,Chen ^[1] ; Steven G,Allen ^[2] ; Ajaya Kumar,Reka ^[3] ; Weiyi,Qian ^[4] ; Shuo,Han ^[5] ; Jianing,Zhao ^[6] ; Liwei,Bao ^[3] ; Venkateshwar G,Keshamouni ^[7] ; Sofia D,Merajver ^[8] ; Jianping,Fu ^[9]

作者单位： Department of Mechanical Engineering, University of Michigan, Ann Arbor, MI, 48109, USA.;Department of Mechanical and Aerospace Engineering, New York University, New York, NY, 10012, USA. ^[1] Program in Cellular and Molecular Biology, University of Michigan, Ann Arbor, MI, 48109, USA.;Medical Scientist Training Program, University of Michigan, Ann Arbor, MI, 48109, USA. ^[2] Department of Internal Medicine, University of Michigan, Ann Arbor, MI, 48109, USA. ^[3] Department of Mechanical and Aerospace Engineering, New York University, New York, NY, 10012, USA. ^[4] Department of Mechanical Engineering, University of Michigan, Ann Arbor, MI, 48109, USA. ^[5] Department of Mechanical Engineering, University of Michigan, Ann Arbor, MI, 48109, USA.;School of Advanced Engineering, Beihang University, Beijing, 100191, China. ^[6] Department of Internal Medicine, University of Michigan, Ann Arbor, MI, 48109, USA. vkeshamo@med.umich.edu.;University of Michigan Comprehensive Cancer Center, University of Michigan, Ann Arbor, MI, 48109, USA. vkeshamo@med.umich.edu. ^[7] Department of Internal Medicine, University of Michigan, Ann Arbor, MI, 48109, USA. smerajve@umich.edu.;University of Michigan Comprehensive Cancer Center, University of Michigan, Ann Arbor, MI, 48109, USA. smerajve@umich.edu. ^[8] Department of Mechanical Engineering, University of Michigan, Ann Arbor, MI, 48109, USA. jpfu@umich.edu.;Department of Biomedical Engineering, University of Michigan, Ann Arbor, MI, 48109, USA. jpfu@umich.edu.;Department of Cell and Developmental Biology, University of Michigan, Ann Arbor, MI, 48109, USA. jpfu@umich.edu.;Michigan Center for Integrative Research in Critical Care, University of Michigan, Ann Arbor, MI, 48109, USA. jpfu@umich.edu. ^[9]

关键词 Adhesion Breast cancer Circulating tumor cells Lung cancer Metastasis Microfluidics