换一批A combination of TERT promoter mutation and MGMT methylation status predicts clinically relevant subgroups of newly diagnosed glioblastomas.
第一作者：
Hideyuki,Arita
第一单位：
Division of Brain Tumor Translational Research, National Cancer Center Research Institute, 5-1-1 Tsukiji, Chuo-ku, Tokyo, 104-0045, Japan. neuro.husky@gmail.com.;Department of Neurosurgery, Osaka University Graduate School of Medicine, Osaka, Japan. neuro.husky@gmail.com.
作者：
Hideyuki,Arita [1]
;
Kai,Yamasaki [2]
;
Yuko,Matsushita [3]
;
Taishi,Nakamura [4]
;
Asanao,Shimokawa [5]
;
Hirokazu,Takami [6]
;
Shota,Tanaka [7]
;
Akitake,Mukasa [7]
;
Mitsuaki,Shirahata [8]
;
Saki,Shimizu [9]
;
Kaori,Suzuki [9]
;
Kuniaki,Saito [9]
;
Keiichi,Kobayashi [9]
;
Fumi,Higuchi [10]
;
Takeo,Uzuka [10]
;
Ryohei,Otani [10]
;
Kaoru,Tamura [11]
;
Kazutaka,Sumita [11]
;
Makoto,Ohno [12]
;
Yasuji,Miyakita [12]
;
Naoki,Kagawa [13]
;
Naoya,Hashimoto [13]
;
Ryusuke,Hatae [14]
;
Koji,Yoshimoto [14]
;
Naoki,Shinojima [15]
;
Hideo,Nakamura [15]
;
Yonehiro,Kanemura [16]
;
Yoshiko,Okita [17]
;
Manabu,Kinoshita [18]
;
Kenichi,Ishibashi [19]
;
Tomoko,Shofuda [20]
;
Yoshinori,Kodama [21]
;
Kanji,Mori [22]
;
Yusuke,Tomogane [23]
;
Junya,Fukai [24]
;
Koji,Fujita [24]
;
Yuzo,Terakawa [25]
;
Naohiro,Tsuyuguchi [25]
;
Shusuke,Moriuchi [26]
;
Masahiro,Nonaka [17]
;
Hiroyoshi,Suzuki [27]
;
Makoto,Shibuya [28]
;
Taketoshi,Maehara [11]
;
Nobuhito,Saito [7]
;
Motoo,Nagane [9]
;
Nobutaka,Kawahara [29]
;
Keisuke,Ueki [10]
;
Toshiki,Yoshimine [13]
;
Etsuo,Miyaoka [5]
;
Ryo,Nishikawa [8]
;
Takashi,Komori [30]
;
Yoshitaka,Narita [12]
;
Koichi,Ichimura [31]
作者单位：
Division of Brain Tumor Translational Research, National Cancer Center Research Institute, 5-1-1 Tsukiji, Chuo-ku, Tokyo, 104-0045, Japan. neuro.husky@gmail.com.;Department of Neurosurgery, Osaka University Graduate School of Medicine, Osaka, Japan. neuro.husky@gmail.com.
[1]
Division of Brain Tumor Translational Research, National Cancer Center Research Institute, 5-1-1 Tsukiji, Chuo-ku, Tokyo, 104-0045, Japan.;Department of Pediatric Hematology and Oncology, Osaka City General Hospital, Osaka, Japan.
[2]
Division of Brain Tumor Translational Research, National Cancer Center Research Institute, 5-1-1 Tsukiji, Chuo-ku, Tokyo, 104-0045, Japan.;Department of Neurosurgery and Neuro-Oncology, National Cancer Center Hospital, Tokyo, Japan.
[3]
Division of Brain Tumor Translational Research, National Cancer Center Research Institute, 5-1-1 Tsukiji, Chuo-ku, Tokyo, 104-0045, Japan.;Department of Neurosurgery, Graduate School of Medicine, Yokohama City University, Yokohama, Japan.
[4]
Department of Mathematics, Faculty of Science, Tokyo University of Science, Tokyo, Japan.
[5]
Division of Brain Tumor Translational Research, National Cancer Center Research Institute, 5-1-1 Tsukiji, Chuo-ku, Tokyo, 104-0045, Japan.;Department of Neurosurgery, The University of Tokyo, Tokyo, Japan.
[6]
Department of Neurosurgery, The University of Tokyo, Tokyo, Japan.
[7]
Department of Neuro-Oncology/Neurosurgery, Saitama Medical University International Medical Center, Saitama, Japan.
[8]
Department of Neurosurgery, Kyorin University Faculty of Medicine, Tokyo, Japan.
[9]
Department of Neurosurgery, Dokkyo Medical University, Tochigi, Japan.
[10]
Department of Neurosurgery, Tokyo Medical and Dental University, Tokyo, Japan.
[11]
Department of Neurosurgery and Neuro-Oncology, National Cancer Center Hospital, Tokyo, Japan.
[12]
Department of Neurosurgery, Osaka University Graduate School of Medicine, Osaka, Japan.
[13]
Department of Neurosurgery, Kyushu University Graduate School of Medical Science, Fukuoka, Japan.
[14]
Department of Neurosurgery, Graduate School of Life Sciences, Kumamoto University, Kumamoto, Japan.
[15]
Division of Regenerative Medicine, Institute for Clinical Research, Osaka National Hospital, National Hospital Organization, Osaka, Japan.;Department of Neurosurgery, National Hospital Organization Osaka National Hospital, Osaka, Japan.
[16]
Department of Neurosurgery, National Hospital Organization Osaka National Hospital, Osaka, Japan.
[17]
Department of Neurosurgery, Osaka Medical Center for Cancer and Cardiovascular Diseases, Osaka, Japan.
[18]
Department of Neurosurgery, Osaka City General Hospital, Osaka, Japan.
[19]
Division of Stem Cell Research, Institute for Clinical Research, Osaka National Hospital, National Hospital Organization, Osaka, Japan.
[20]
Central Laboratory and Surgical Pathology, Osaka National Hospital, National Hospital Organization, Osaka, Japan.
[21]
Department of Neurosurgery, Kansai Rosai Hospital, Hyogo, Japan.
[22]
Department of Neurosurgery, Hyogo College of Medicine, Hyogo, Japan.
[23]
Department of Neurological Surgery, Wakayama Medical University, Wakayama, Japan.
[24]
Department of Neurosurgery, Osaka City University Graduate School of Medicine, Osaka, Japan.
[25]
Department of Neurosurgery, Rinku General Medical Center, Izumisano, Osaka, Japan.
[26]
Department of Pathology and Laboratory Medicine, National Hospital Organization, Sendai Medical Center, Sendai, Japan.
[27]
Central Laboratory, Hachioji Medical Center, Tokyo Medical University, Tokyo, Japan.
[28]
Department of Neurosurgery, Graduate School of Medicine, Yokohama City University, Yokohama, Japan.
[29]
Department of Laboratory Medicine and Pathology (Neuropathology), Tokyo Metropolitan Neurological Hospital, Tokyo, Japan.
[30]
Division of Brain Tumor Translational Research, National Cancer Center Research Institute, 5-1-1 Tsukiji, Chuo-ku, Tokyo, 104-0045, Japan. kichimur@ncc.go.jp.
[31]
主题词
成年人(Adult);抗肿瘤药, 烷基化(Antineoplastic Agents, Alkylating);脑肿瘤(Brain Neoplasms);队列研究(Cohort Studies);综合疗法(Combined Modality Therapy);DNA甲基化(DNA Methylation);DNA修饰甲基酶类(DNA Modification Methylases);DNA修复酶类(DNA Repair Enzymes);达卡巴嗪(Dacarbazine);女(雌)性(Female);胶质母细胞瘤(Glioblastoma);人类(Humans);异柠檬酸脱氢酶(Isocitrate Dehydrogenase);日本(Japan);男(雄)性(Male);中年人(Middle Aged);突变(Mutation);启动区, 遗传(Promoter Regions, Genetic);存活率分析(Survival Analysis);末端转移酶端粒(Telomerase);肿瘤抑制蛋白质类(Tumor Suppressor Proteins)
DOI
10.1186/s40478-016-0351-2
PMID
27503138
发布时间
2024-03-25
- 浏览68
Acta neuropathologica communications
Acta neuropathologica communications
2016年4卷1期
79页
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