Towards the development of an enzyme replacement therapy for the metabolic disorder propionic acidemia.
第一作者:
Mahnaz,Darvish-Damavandi
第一单位:
Department of Pharmacy, Faculty of Science, National University of Singapore, Singapore.
作者:
关键词
CPPs, cell penetrating peptidesCoA, coenzyme-AERT, enzyme replacement therapyEnzyme replacement therapyHis-tag, six histidines tagLAD, lipoamine dehydrogenaseMPP, mitochondrial processing peptidaseMTS, mitochondria targeting sequencesMitochondrial targeting sequencesPA, propionic acidemiaPCC, propionyl coenzyme-A carboxylasePCCA, PCCα subunitPCCB, PCCβ subunitPP-CoA, propionyl coenzyme-APropionic acidemiaPropionyl coenzyme-A carboxylaseProtein transduction domainsUPLC-MS/MS, ultra performance liquid chromatography tandem mass spectrometry
DOI
10.1016/j.ymgmr.2016.06.009
PMID
27504265
发布时间
2020-10-01
- 浏览2
Molecular genetics and metabolism reports
2016年8卷
51-60页
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