NUMB negatively regulates the epithelial-mesenchymal transition of triple-negative breast cancer by antagonizing Notch signaling.
第一作者:
Jianchao,Zhang
第一单位:
Shenzhen Key Laboratory for Molecular Biology of Neural Development, Guangdong Key Laboratory of Nanomedicine, Institute of Biomedicine and Biotechnology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, Guangdong 518055, China.
作者:
医学主题词
动物(Animals);乳房(Breast);细胞系, 肿瘤(Cell Line, Tumor);细胞运动(Cell Movement);细胞增殖(Cell Proliferation);上皮-间质转化(Epithelial-Mesenchymal Transition);女(雌)性(Female);基因表达调控, 肿瘤(Gene Expression Regulation, Neoplastic);HEK293细胞(HEK293 Cells);人类(Humans);慢病毒属(Lentivirus);膜蛋白质类(Membrane Proteins);小鼠(Mice);小鼠, 近交BALB C(Mice, Inbred BALB C);小鼠, 裸(Mice, Nude);肿瘤转移(Neoplasm Metastasis);肿瘤移植(Neoplasm Transplantation);神经组织蛋白质类(Nerve Tissue Proteins);表型(Phenotype);预后(Prognosis);受体, Notch1(Receptor, Notch1);信号传导(Signal Transduction);干细胞(Stem Cells);肿瘤抑制蛋白质p53(Tumor Suppressor Protein p53)
DOI
10.18632/oncotarget.11062
PMID
27506933
发布时间
2023-12-13
- 浏览4
Oncotarget
61036-61053页
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