Three-dimensional modelling identifies novel genetic dependencies associated with breast cancer progression in the isogenic MCF10 model.
第一作者:
Sarah L,Maguire
第一单位:
The Breast Cancer Now Toby Robins Research Centre, Division of Breast Cancer, The Institute of Cancer Research, London, UK.
作者:
医学主题词
乳腺肿瘤(Breast Neoplasms);癌, 导管, 乳腺(Carcinoma, Ductal, Breast);癌, 导管内, 非浸润性(Carcinoma, Intraductal, Noninfiltrating);细胞系, 肿瘤(Cell Line, Tumor);细胞转化, 肿瘤(Cell Transformation, Neoplastic);I类磷脂酰肌醇3-激酶类(Class I Phosphatidylinositol 3-Kinases);DNA, 肿瘤(DNA, Neoplasm);疾病恶化(Disease Progression);女(雌)性(Female);基因表达调控, 肿瘤(Gene Expression Regulation, Neoplastic);基因组(Genome);高通量核苷酸序列分析(High-Throughput Nucleotide Sequencing);人类(Humans);模型, 生物学(Models, Biological);突变(Mutation);磷酸肌醇3-激酶类(Phosphatidylinositol 3-Kinases);序列分析, DNA(Sequence Analysis, DNA);球形体, 细胞(Spheroids, Cellular);肿瘤抑制蛋白质p53(Tumor Suppressor Protein p53)
DOI
10.1002/path.4778
PMID
27512948
发布时间
2025-05-30
- 浏览28
The Journal of pathology
315-328页
相似文献
- 中文期刊
- 外文期刊
- 学位论文
- 会议论文


换一批



