Self-Assembling Doxorubicin Prodrug Forming Nanoparticles and Effectively Reversing Drug Resistance In Vitro and In Vivo.

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第一作者： Xiaoman,Mao

第一单位： College of Chemical and Biological Engineering, Zhejiang University, Hangzhou, 310027, China.

作者： Xiaoman,Mao ^[1] ; Jingxing,Si ^[2] ; Qian,Huang ^[1] ; Xuanrong,Sun ^[2] ; Qianzhi,Zhang ^[3] ; Youqing,Shen ^[1] ; Jianbin,Tang ^[2] ; Xiangrui,Liu ^[1] ; Meihua,Sui ^[1]

作者单位： College of Chemical and Biological Engineering, Zhejiang University, Hangzhou, 310027, China. ^[1] Center for Cancer Biology and Innovative Therapeutics, Key Laboratory of Tumor Molecular Diagnosis and Individualized Medicine of Zhejiang Province, Clinical Research Institute, Zhejiang Provincial People's Hospital, Hangzhou, 310014, China. ^[2] Collaborative Innovation Center for Yangtze River Delta Region Green Pharmaceuticals, Zhejiang University of Technology, Hangzhou, 310014, China. ^[3] College of Chemical and Biological Engineering, Zhejiang University, Hangzhou, 310027, China. suim@zju.edu.cn. ^[4] Center for Cancer Biology and Innovative Therapeutics, Key Laboratory of Tumor Molecular Diagnosis and Individualized Medicine of Zhejiang Province, Clinical Research Institute, Zhejiang Provincial People's Hospital, Hangzhou, 310014, China. suim@zju.edu.cn. ^[5]

关键词 doxorubicin multidrug resistance nanoparticles self-assembly sensitization