换一批Cystatin C Shifts APP Processing from Amyloid-β Production towards Non-Amyloidgenic Pathway in Brain Endothelial Cells.
第一作者：
Xia-Fei,Wang
第一单位：
Department of Developmental Cell Biology, Key Laboratory of Cell Biology, Ministry of Public Health, and Key Laboratory of Medical Cell Biology, Ministry of Education, China Medical University, 77 Puhe Road, Shenbei New District, Shenyang 110122, China.
作者：
医学主题词
阿尔茨海默病(Alzheimer Disease);淀粉样前体蛋白分泌酶类(Amyloid Precursor Protein Secretases);淀粉样β肽类(Amyloid beta-Peptides);淀粉样β蛋白前体(Amyloid beta-Protein Precursor);天冬氨酸内肽酶类(Aspartic Acid Endopeptidases);脑(Brain);细胞, 培养的(Cells, Cultured);半胱氨酸蛋白酶抑制物C(Cystatin C);半胱氨酸蛋白酶抑制剂(Cysteine Proteinase Inhibitors);减量调节(Down-Regulation);内皮细胞(Endothelial Cells);人类(Humans);膜蛋白质类(Membrane Proteins);代谢网络和途径(Metabolic Networks and Pathways);肽碎片(Peptide Fragments);蛋白酶体内肽酶复合物(Proteasome Endopeptidase Complex);预防和防护用药(Protective Agents);蛋白质加工, 转译后(Protein Processing, Post-Translational);RNA, 信使(RNA, Messenger);抗衰老酶1(Sirtuin 1);增量调节(Up-Regulation)
DOI
10.1371/journal.pone.0161093
PMID
27532339
发布时间
2024-03-27
- 浏览5
PloS one
e0161093页
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