换一批Neferine inhibits proliferation and collagen synthesis induced by high glucose in cardiac fibroblasts and reduces cardiac fibrosis in diabetic mice.
第一作者：
Xue,Liu
第一单位：
The Key Laboratory of Cardiovascular Remodeling and Function Research, Chinese Ministry of Education and Chinese Ministry of Public Health, Qilu Hospital, Shandong University, Jinan, Shandong 250012, China.;Department of Traditional Chinese Medicine, Qilu Hospital, Shandong University, Jinan, Shandong 250012, China.
作者：
医学主题词
动物(Animals);苄异喹啉类(Benzylisoquinolines);细胞周期(Cell Cycle);细胞分化(Cell Differentiation);细胞运动(Cell Movement);细胞增殖(Cell Proliferation);胶原(Collagen);糖尿病, 实验性(Diabetes Mellitus, Experimental);糖尿病, 1型(Diabetes Mellitus, Type 1);中草药(Drugs, Chinese Herbal);细胞外信号调节MAP激酶类(Extracellular Signal-Regulated MAP Kinases);成纤维细胞(Fibroblasts);纤维化(Fibrosis);葡萄糖(Glucose);心率(Heart Rate);男(雄)性(Male);小鼠(Mice);小鼠, 近交C57BL(Mice, Inbred C57BL);心肌(Myocardium);信号传导(Signal Transduction);Smad蛋白质类(Smad Proteins);转化生长因子β1(Transforming Growth Factor beta1);p38丝裂原活化蛋白激酶类(p38 Mitogen-Activated Protein Kinases)
DOI
10.18632/oncotarget.11225
PMID
27533252
发布时间
2022-06-20
- 浏览7
Oncotarget
61703-61715页
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