Neutral Sphingomyelinase-2 Deficiency Ameliorates Alzheimer's Disease Pathology and Improves Cognition in the 5XFAD Mouse.-论文-万方医学网

作者： Michael B,Dinkins ^[1] ; John,Enasko ^[1] ; Caterina,Hernandez ^[2] ; Guanghu,Wang ^[1] ; Jina,Kong ^[1] ; Inas,Helwa ^[3] ; Yutao,Liu ^[3] ; Alvin V,Terry ^[2] ; Erhard,Bieberich ^[4]

作者单位： Department of Neuroscience and Regenerative Medicine. ^[1] Department of Pharmacology and Toxicology, and. ^[2] Department of Cellular Biology and Anatomy, The Medical College of Georgia, Augusta University, Augusta, Georgia 30912. ^[3] Department of Neuroscience and Regenerative Medicine, ebieberich@augusta.edu. ^[4]

主题词阿尔茨海默病(Alzheimer Disease);淀粉样β肽类(Amyloid beta-Peptides);淀粉样β蛋白前体(Amyloid beta-Protein Precursor);动物(Animals);动物, 新生(Animals, Newborn);细胞, 培养的(Cells, Cultured);认知障碍(Cognition Disorders);疾病模型, 动物(Disease Models, Animal);外泌体(Exosomes);女(雌)性(Female);基因表达调控(Gene Expression Regulation);人类(Humans);脂类代谢(Lipid Metabolism);男(雄)性(Male);小鼠(Mice);小鼠, 近交C57BL(Mice, Inbred C57BL);小鼠, 转基因(Mice, Transgenic);突变(Mutation);神经胶质(Neuroglia);早老素1(Presenilin-1);鞘磷脂磷酸二酯酶(Sphingomyelin Phosphodiesterase)

DOI 10.1523/JNEUROSCI.1429-16.2016

PMID 27535912

发布时间 2018-11-13

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Neutral Sphingomyelinase-2 Deficiency Ameliorates Alzheimer's Disease Pathology and Improves Cognition in the 5XFAD Mouse.

The Journal of neuroscience

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Neutral Sphingomyelinase-2 Deficiency Ameliorates Alzheimer's Disease Pathology and Improves Cognition in the 5XFAD Mouse.

The Journal of neuroscience

相似文献

The Journal of neuroscience

相关期刊

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