Histone deacetylase inhibitors induce invasion of human melanoma cells in vitro via differential regulation of N-cadherin expression and RhoA activity.
作者:
主题词
抗肿瘤药(Antineoplastic Agents);细胞凋亡(Apoptosis);丁酸盐类(Butyrates);钙黏着糖蛋白类(Cadherins);细胞系, 肿瘤(Cell Line, Tumor);基因表达调控, 肿瘤(Gene Expression Regulation, Neoplastic);组蛋白脱乙酰基酶抑制剂(Histone Deacetylase Inhibitors);人类(Humans);羟肟酸类(Hydroxamic Acids);黑色素瘤(Melanoma);肿瘤侵润(Neoplasm Invasiveness);RNA干扰(RNA Interference);RNA, 小分子干扰(RNA, Small Interfering);丙戊酸(Valproic Acid);ρA GTP结合蛋白质(rhoA GTP-Binding Protein)
DOI
10.1186/s12885-016-2693-3
PMID
27549189
发布时间
2018-12-02
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BMC cancer
667页
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