换一批
换一批Genetic Risk Score Mendelian Randomization Shows that Obesity Measured as Body Mass Index, but not Waist:Hip Ratio, Is Causal for Endometrial Cancer.
第一作者：
Jodie N,Painter
第一单位：
Department of Genetics and Computational Biology, QIMR Berghofer Medical Research Institute, Brisbane, Australia.
作者：
Jodie N,Painter [1]
;
Tracy A,O'Mara [1]
;
Louise,Marquart [1]
;
Penelope M,Webb [2]
;
John,Attia [3]
;
Sarah E,Medland [1]
;
Timothy,Cheng [4]
;
Joe,Dennis [5]
;
Elizabeth G,Holliday [2]
;
Mark,McEvoy [3]
;
Rodney J,Scott [3]
;
Shahana,Ahmed [2]
;
Catherine S,Healey [6]
;
Mitul,Shah [7]
;
Maggie,Gorman [8]
;
Lynn,Martin [9]
;
Shirley V,Hodgson [9]
;
Matthias W,Beckmann [9]
;
Arif B,Ekici [4]
;
Peter A,Fasching [4]
;
Alexander,Hein [10]
;
Matthias,Rübner [11]
;
Kamila,Czene [12]
;
Hatef,Darabi [11]
;
Per,Hall [13]
;
Jingmei,Li [11]
;
Thilo,Dörk [11]
;
Matthias,Dürst [14]
;
Peter,Hillemanns [14]
;
Ingo B,Runnebaum [14]
;
Frederic,Amant [14]
;
Daniela,Annibali [15]
;
Jeroen,Depreeuw [16]
;
Diether,Lambrechts [17]
;
Patrick,Neven [16]
;
Julie M,Cunningham [18]
;
Sean C,Dowdy [18]
;
Ellen L,Goode [18]
;
Brooke L,Fridley [19]
;
Stacey J,Winham [20]
;
Tormund S,Njølstad [19]
;
Helga B,Salvesen [20]
;
Jone,Trovik [18]
;
Henrica M J,Werner [21]
;
Katie A,Ashton [22]
;
Geoffrey,Otton [23]
;
Anthony,Proietto [24]
;
Miriam,Mints [23]
;
Emma,Tham [25]
;
Manjeet K,Bolla [26]
;
Kyriaki,Michailidou [25]
;
Qin,Wang [26]
;
Jonathan P,Tyrer [25]
;
John L,Hopper [26]
;
Julian,Peto [25]
;
Anthony J,Swerdlow [26]
;
Barbara,Burwinkel [2]
;
Hermann,Brenner [7]
;
Alfons,Meindl [8]
;
Hiltrud,Brauch [27]
;
Annika,Lindblom [27]
;
Jenny,Chang-Claude [28]
;
Fergus J,Couch [5]
;
Graham G,Giles [5]
;
Vessela N,Kristensen [5]
;
Angela,Cox [9]
;
Paul D P,Pharoah [29]
;
Ian,Tomlinson [30]
;
Alison M,Dunning [31]
;
Douglas F,Easton [32]
;
Deborah J,Thompson [33]
;
Amanda B,Spurdle [34]
;
AOCS Group [35]
;
for RENDOCAS [36]
;
National Study of Endometrial Cancer Genetics Group (NSECG) [37]
;
Australian National Endometrial Cancer Study Group (ANECS) [38]
作者单位：
Department of Genetics and Computational Biology, QIMR Berghofer Medical Research Institute, Brisbane, Australia.
[1]
Hunter Medical Research Institute, John Hunter Hospital, Newcastle, Australia.
[2]
Centre for Clinical Epidemiology and Biostatistics, School of Medicine and Public Health, University of Newcastle, Australia.
[3]
Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom.
[4]
Department of Public Health and Primary Care, Centre for Cancer Genetic Epidemiology, University of Cambridge, Cambridge, United Kingdom.
[5]
Hunter Area Pathology Service, John Hunter Hospital, Newcastle, Australia.
[6]
Centre for Information Based Medicine, University of Newcastle, Australia.
[7]
School of Biomedical Sciences and Pharmacy, University of Newcastle, Newcastle, Australia.
[8]
Department of Oncology, Centre for Cancer Genetic Epidemiology, University of Cambridge, Cambridge, United Kingdom.
[9]
Department of Clinical Genetics, St George's, University of London, London, United Kingdom.
[10]
Department of Gynecology and Obstetrics, University Hospital Erlangen, Friedrich-Alexander University Erlangen-Nuremberg, Erlangen, Germany.
[11]
Institute of Human Genetics, University Hospital Erlangen, Friedrich-Alexander-University Erlangen-Nuremberg, Erlangen, Germany.
[12]
Department of Medicine, Division of Hematology/Oncology, David Geffen School of Medicine, University of California at Los Angeles, Los Angeles, California.
[13]
Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.
[14]
Hannover Medical School, Gynaecology Research Unit, Hannover, Germany.
[15]
Department of Gynaecology, Jena University Hospital, Friedrich Schiller University, Jena, Germany.
[16]
Hannover Medical School, Clinics of Gynaecology and Obstetrics, Hannover, Germany.
[17]
Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, University Hospitals, KU Leuven - University of Leuven, Leuven, Belgium.
[18]
Vesalius Research Center, VIB, Leuven, Belgium.
[19]
Department of Oncology, Laboratory for Translational Genetics, University Hospitals Leuven, Leuven, Belgium.
[20]
Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota.
[21]
Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, Mayo Clinic, Rochester, Minnesota.
[22]
Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota.
[23]
Department of Biostatistics, University of Kansas Medical Center, Kansas City, Kansas.
[24]
Department of Clinical Science, Centre for Cancer Biomarkers, The University of Bergen, Bergen, Norway.
[25]
Department of Obstetrics and Gynecology, Haukeland University Hospital, Bergen, Norway.
[26]
School of Medicine and Public Health, University of Newcastle, Newcastle, Australia.
[27]
Department of Women's and Children's Health, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden.
[28]
Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Victoria, Australia.
[29]
London School of Hygiene and Tropical Medicine, London, United Kingdom.
[30]
Division of Genetics and Epidemiology, Institute of Cancer Research, London, United Kingdom.
[31]
Division of Breast Cancer Research, Institute of Cancer Research, London, United Kingdom.
[32]
Department of Gynecology and Obstetrics, Molecular Biology of Breast Cancer, University of Heidelberg, Heidelberg, Germany.
[33]
Molecular Epidemiology Group, German Cancer Research Center (DKFZ), Heidelberg, Germany.
[34]
Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), Heidelberg, Germany.
[35]
Division of Preventive Oncology, German Cancer Research Center (DKFZ) and National Center for Tumor Diseases (NCT), Heidelberg, Germany.
[36]
German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany.
[37]
Department of Obstetrics and Gynecology, Division of Tumor Genetics, Technical University of Munich, Munich, Germany.
[38]
Dr. Margarete Fischer-Bosch-Institute of Clinical Pharmacology, Stuttgart, Germany.
[39]
University of Tübingen, Tübingen, Germany.
[40]
Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden.
[41]
Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany.
[42]
University Cancer Center Hamburg (UCCH), University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
[43]
Cancer Epidemiology Centre, Cancer Council Victoria, Melbourne, Victoria, Australia.
[44]
Department of Epidemiology and Preventive Medicine, Monash University, Melbourne, Victoria, Australia.
[45]
Department of Genetics, Institute for Cancer Research, The Norwegian Radium Hospital, Oslo, Norway.
[46]
The K.G. Jebsen Center for Breast Cancer Research, Institute for Clinical Medicine, Faculty of Medicine, University of Oslo, Oslo, Norway.
[47]
Department of Clinical Molecular Oncology, Division of Medicine, Akershus University Hospital, Lørenskog, Norway.
[48]
Sheffield Cancer Research, Department of Oncology, University of Sheffield, Sheffield, United Kingdom.
[49]
主题词
人体质量指数(Body Mass Index);子宫内膜肿瘤(Endometrial Neoplasms);女(雌)性(Female);疾病遗传易感性(Genetic Predisposition to Disease);人类(Humans);孟德尔随机化分析(Mendelian Randomization Analysis);肥胖症(Obesity);多态性, 单核苷酸(Polymorphism, Single Nucleotide);腰臀比(Waist-Hip Ratio)
DOI
10.1158/1055-9965.EPI-16-0147
PMID
27550749
发布时间
2024-02-14
- 浏览58
Cancer epidemiology, biomarkers & prevention
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