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Preservation Analysis of Macrophage Gene Coexpression Between Human and Mouse Identifies PARK2 as a Genetically Controlled Master Regulator of Oxidative Phosphorylation in Humans.

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第一作者： Veronica,Codoni

第一单位： Sorbonne Universités, Université Pierre et Marie Curie, Paris 06, Institut National de la Santé et de la Recherche Médicale, Unité Mixte de Recherche en Santé 1166, F-75013 Paris, France Institute for Cardiometabolism and Nutrition, F-75013 Paris, France.

作者： Veronica,Codoni ^[1] ; Yuna,Blum ^[2] ; Mete,Civelek ^[3] ; Carole,Proust ^[1] ; Oscar,Franzén ^[4] ; Cardiogenics Consortium ^[5] ; IDEM Leducq Consortium CADGenomics ^[1] ; Johan L M,Björkegren ^[1] ; Wilfried,Le Goff ^[2] ; Francois,Cambien ^[6] ; Aldons J,Lusis ; David-Alexandre,Trégouët

作者单位： Sorbonne Universités, Université Pierre et Marie Curie, Paris 06, Institut National de la Santé et de la Recherche Médicale, Unité Mixte de Recherche en Santé 1166, F-75013 Paris, France Institute for Cardiometabolism and Nutrition, F-75013 Paris, France. ^[1] Division of Cardiology, Department of Medicine, David Geffen School of Medicine, University of California, Los Angeles, California 90095. ^[2] Division of Cardiology, Department of Medicine, David Geffen School of Medicine, University of California, Los Angeles, California 90095 Department of Biomedical Engineering, Center for Public Health Genomics, University of Virginia, Charlottesville, Virginia 22908. ^[3] Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, New York 10029 Icahn Institute of Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, New York 10029. ^[4] Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, New York 10029 Icahn Institute of Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, New York 10029 Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm 141 52, Sweden. ^[5] Sorbonne Universités, Université Pierre et Marie Curie, Paris 06, Institut National de la Santé et de la Recherche Médicale, Unité Mixte de Recherche en Santé 1166, F-75013 Paris, France Institute for Cardiometabolism and Nutrition, F-75013 Paris, France david.tregouet@upmc.fr. ^[6]

关键词 cross-species comparison eQTL analysis gene expression network analysis macrophages trans genetic effects