Stability behaviour of antiretroviral drugs and their combinations. 4: Characterization of degradation products of tenofovir alafenamide fumarate and comparison of its degradation and stability behaviour with tenofovir disoproxil fumarate.

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作者： Vijaya Madhyanapu,Golla ^[1] ; Moolchand,Kurmi ^[1] ; Karimullah,Shaik ^[1] ; Saranjit,Singh ^[2]

作者单位： Department of Pharmaceutical Analysis, National Institute of Pharmaceutical Education and Research (NIPER), Sector 67(,) S.A.S. Nagar 160 062, Punjab, India. ^[1] Department of Pharmaceutical Analysis, National Institute of Pharmaceutical Education and Research (NIPER), Sector 67(,) S.A.S. Nagar 160 062, Punjab, India. Electronic address: ssingh@niper.ac.in. ^[2]

关键词 LC-HRMS MS(n)Prodrug Tenofovir alafenamide fumarate Tenofovir disoproxil fumarate

主题词抗HIV药(Anti-HIV Agents);抗逆转录病毒药(Anti-Retroviral Agents);药物稳定性(Drug Stability);人类(Humans);药物前体(Prodrugs)

DOI 10.1016/j.jpba.2016.08.022

PMID 27589032

发布时间 2017-10-08

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