换一批Phase I Study Evaluating WEE1 Inhibitor AZD1775 As Monotherapy and in Combination With Gemcitabine, Cisplatin, or Carboplatin in Patients With Advanced Solid Tumors.
第一作者：
Suzanne,Leijen
第一单位：
Suzanne Leijen, Robin M.J.M. van Geel, and Jan H.M. Schellens, The Netherlands Cancer Institute, Amsterdam; Jan H.M. Schellens, Utrecht University, Utrecht, the Netherlands; Anna C. Pavlick, New York University Medical Center, New York, NY; Lee Rosen, University of California Los Angeles, Santa Monica, CA; Raymond Lam, Shelonitda Rose, Mark A. Lee, Tomoko Freshwater, and Stuart Shumway, Merck, Kenilworth, NJ; Geoffrey I. Shapiro, Dana-Farber Cancer Institute, Boston, MA; Albiruni R. Abdul Razak and Amit M. Oza, Princess Margaret Hospital, Toronto, Ontario, Canada; Raoul Tibes, University Hospital of Würzburg, Würzburg; Tim Demuth, Sandoz AG, Holzkirchen, Germany; and Li Wen Liang, Merck Sharp & Dohme R&D, Beijing, China.
作者：
医学主题词
成年人(Adult);老年人(Aged);方差分析(Analysis of Variance);抗肿瘤联合化疗方案(Antineoplastic Combined Chemotherapy Protocols);卡铂(Carboplatin);顺铂(Cisplatin);脱氧胞苷(Deoxycytidine);无病生存(Disease-Free Survival);剂量效应关系, 药物(Dose-Response Relationship, Drug);用药计划表(Drug Administration Schedule);女(雌)性(Female);人类(Humans);男(雄)性(Male);最大耐受剂量(Maximum Tolerated Dose);中年人(Middle Aged);肿瘤(Neoplasms);预后(Prognosis);吡唑类(Pyrazoles);嘧啶类(Pyrimidines);嘧啶酮类(Pyrimidinones);危险性评估(Risk Assessment);存活率分析(Survival Analysis);治疗结果(Treatment Outcome)
DOI
10.1200/JCO.2016.67.5991
PMID
27601554
发布时间
2023-11-10
基金项目
R01 CA178979/CA/NCI NIH HHS/United States
- 浏览8
Journal of clinical oncology
4371-4380页
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