Pathological Ace2-to-Ace enzyme switch in the stressed heart is transcriptionally controlled by the endothelial Brg1-FoxM1 complex.

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第一作者： Jin,Yang

第一单位： Krannert Institute of Cardiology and Division of Cardiology, Department of Medicine, Indiana University School of Medicine, Indianapolis, IN 46202; Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, IN 46202; Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, IN 46202;

作者： Jin,Yang ^[1] ; Xuhui,Feng ^[1] ; Qiong,Zhou ^[1] ; Wei,Cheng ^[1] ; Ching,Shang ^[2] ; Pei,Han ^[2] ; Chiou-Hong,Lin ^[2] ; Huei-Sheng Vincent,Chen ^[3] ; Thomas,Quertermous ^[2] ; Ching-Pin,Chang ^[4]

作者单位： Krannert Institute of Cardiology and Division of Cardiology, Department of Medicine, Indiana University School of Medicine, Indianapolis, IN 46202; Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, IN 46202; Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, IN 46202; ^[1] Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, CA 94305; ^[2] Del E. Webb Neuroscience, Aging, and Stem Cell Research Center, Sanford/Burnham Medical Research Institute, La Jolla, CA 92037. ^[3] Krannert Institute of Cardiology and Division of Cardiology, Department of Medicine, Indiana University School of Medicine, Indianapolis, IN 46202; Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, IN 46202; Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, IN 46202; changcp@iu.edu. ^[4]

关键词 Brg1 FoxM1 cardiac hypertrophy chromatin remodeling endothelial cells