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RNAseq analysis of heart tissue from mice treated with atenolol and isoproterenol reveals a reciprocal transcriptional response.

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第一作者： Andrea,Prunotto

第一单位： Department of Medical Genetics, University of Lausanne, Rue du Bugnon 27, 1011, Lausanne, Switzerland.;Swiss Institute of Bioinformatics, Lausanne, Switzerland.

作者： Andrea,Prunotto ^[1] ; Brian J,Stevenson ^[2] ; Corinne,Berthonneche ^[3] ; Fanny,Schüpfer ^[3] ; Jacques S,Beckmann ^[4] ; Fabienne,Maurer ^[5] ; Sven,Bergmann ^[6]

作者单位： Department of Medical Genetics, University of Lausanne, Rue du Bugnon 27, 1011, Lausanne, Switzerland.;Swiss Institute of Bioinformatics, Lausanne, Switzerland. ^[1] Swiss Institute of Bioinformatics, Lausanne, Switzerland. ^[2] Service of Medical Genetics, Centre Hospitalier Universitaire Vaudois and University of Lausanne, Rue du Bugnon 27, 1011, Lausanne, Switzerland. ^[3] Department of Medical Genetics, University of Lausanne, Rue du Bugnon 27, 1011, Lausanne, Switzerland.;Swiss Institute of Bioinformatics, Lausanne, Switzerland.;Service of Medical Genetics, Centre Hospitalier Universitaire Vaudois and University of Lausanne, Rue du Bugnon 27, 1011, Lausanne, Switzerland. ^[4] Service of Medical Genetics, Centre Hospitalier Universitaire Vaudois and University of Lausanne, Rue du Bugnon 27, 1011, Lausanne, Switzerland. Fabienne.Maurer@chuv.ch. ^[5] Department of Medical Genetics, University of Lausanne, Rue du Bugnon 27, 1011, Lausanne, Switzerland. Sven.Bergmann@unil.ch.;Swiss Institute of Bioinformatics, Lausanne, Switzerland. Sven.Bergmann@unil.ch.;Department of Integrative Biomedical Sciences, University of Cape Town, Cape Town, South Africa. Sven.Bergmann@unil.ch. ^[6]

关键词 Atenolol Cardiac hypertrophy Isoproterenol Mouse heart RNAseq β-adrenergic system