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首页> Biomaterials> An injectable acellular matrix scaffold with absorbable permeable nanoparticles improves the therapeutic effects of docetaxel on glioblastoma.

An injectable acellular matrix scaffold with absorbable permeable nanoparticles improves the therapeutic effects of docetaxel on glioblastoma.

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作者： He-Lin,Xu ^[1] ; Kai-Li,Mao ^[1] ; Cui-Tao,Lu ^[2] ; Zi-Liang,Fan ^[1] ; Jing-Jing,Yang ^[1] ; Jie,Xu ^[1] ; Pian-Pian,Chen ^[1] ; De-Li,ZhuGe ^[1] ; Bi-Xin,Shen ^[1] ; Bing-Hui,Jin ^[1] ; Jian,Xiao ^[3] ; Ying-Zheng,Zhao ^[4]

作者单位： School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, Zhejiang Province 325035, China. ^[1] The Second Affiliated Hospital, Wenzhou Medical University, Wenzhou, Zhejiang Province 325035, China. Electronic address: lctuua@sina.com. ^[2] School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, Zhejiang Province 325035, China. Electronic address: xfxj2000@126.com. ^[3] School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, Zhejiang Province 325035, China; The Second Affiliated Hospital, Wenzhou Medical University, Wenzhou, Zhejiang Province 325035, China. Electronic address: pharmtds@163.com. ^[4]

关键词 Decellularized brain extracellular matrix Glioma Intratumoral injection Permeable nanoparticles Retention time Sustained release

主题词动物(Animals);抗肿瘤药(Antineoplastic Agents);细胞系, 肿瘤(Cell Line, Tumor);细胞存活(Cell Survival);无细胞系统(Cell-Free System);迟效制剂(Delayed-Action Preparations);药物协同作用(Drug Synergism);乳状剂(Emulsions);细胞外基质(Extracellular Matrix);胶质母细胞瘤(Glioblastoma);注射, 病灶内(Injections, Intralesional);男(雄)性(Male);通透性(Permeability);大鼠(Rats);大鼠, Sprague-Dawley(Rats, Sprague-Dawley);紫杉烷类(Taxoids);治疗结果(Treatment Outcome)

DOI 10.1016/j.biomaterials.2016.08.026

PMID 27614158

发布时间 2018-12-03

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Biomaterials

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