The Thiophene "Sigma-Hole" as a Concept for Preorganized, Specific Recognition of G⋅C Base Pairs in the DNA Minor Groove.

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作者： Pu,Guo ^[1] ; Ananya,Paul ^[1] ; Arvind,Kumar ^[1] ; Abdelbasset A,Farahat ^[1] ; Dhiraj,Kumar ^[2] ; Siming,Wang ^[1] ; David W,Boykin ^[1] ; W David,Wilson ^[1]

作者单位： Department of Chemistry and Center for Diagnostics and Therapeutics, Georgia State University, Atlanta, GA, 30303-3083, USA. ^[1] Department of Pharmaceutical Organic Chemistry, Faculty of Pharmacy, Mansoura University, Mansoura, 35516, Egypt. ^[2] Department of Chemistry and Center for Diagnostics and Therapeutics, Georgia State University, Atlanta, GA, 30303-3083, USA. wdw@gsu.edu. ^[3]

关键词 DNA minor groove N-methylbenzimidazole thiophene bioinformatics biosensors sigma-hole

主题词碱基配对(Base Pairing);阳离子(Cations);DNA(DNA);氢键合(Hydrogen Bonding);模型, 分子(Models, Molecular);静电(Static Electricity);噻吩类(Thiophenes)

DOI 10.1002/chem.201603422

PMID 27624927

发布时间 2024-03-24

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准确一般字义偏差语意偏离译文作用小提交