HIF-1α in Myeloid Cells Promotes Adipose Tissue Remodeling Toward Insulin Resistance.-论文-万方医学网

第一作者： Akiko,Takikawa

第一单位： First Department of Internal Medicine, University of Toyama, Toyama, Japan.

作者： Akiko,Takikawa ^[1] ; Arshad,Mahmood ^[1] ; Allah,Nawaz ^[1] ; Tomonobu,Kado ^[1] ; Keisuke,Okabe ^[1] ; Seiji,Yamamoto ^[2] ; Aminuddin,Aminuddin ^[1] ; Satoko,Senda ^[1] ; Koichi,Tsuneyama ^[3] ; Masashi,Ikutani ^[4] ; Yasuharu,Watanabe ^[5] ; Yoshiko,Igarashi ^[5] ; Yoshinori,Nagai ^[6] ; Kiyoshi,Takatsu ^[5] ; Keiichi,Koizumi ^[7] ; Johji,Imura ^[5] ; Nobuhito,Goda ^[8] ; Masakiyo,Sasahara ^[4] ; Michihiro,Matsumoto ^[3] ; Kumiko,Saeki ^[9] ; Takashi,Nakagawa ^[2] ; Shiho,Fujisaka ^[10] ; Isao,Usui ^[11] ; Kazuyuki,Tobe ^[12]

作者单位： First Department of Internal Medicine, University of Toyama, Toyama, Japan. ^[1] Department of Pathology, University of Toyama, Toyama, Japan. ^[2] Department of Diagnostic Pathology, University of Toyama, Toyama, Japan. ^[3] Department of Pathology and Laboratory Medicine, Institute of Biomedical Sciences, Tokushima University Graduate School, Tokushima, Japan. ^[4] Department of Immunobiology and Pharmacological Genetics, Advanced Biomedicine Genome Pharmaceutical Science, Graduate School of Medicine and Pharmaceutical Science for Research, University of Toyama, Toyama, Japan. ^[5] Division of Kampo Diagnostics, Institute of Natural Medicine, University of Toyama, Toyama, Japan. ^[6] PRESTO, Japan Science and Technology Agency, Saitama, Japan. ^[7] Toyama Prefectural Institute for Pharmaceutical Research, Toyama, Japan. ^[8] Department of Life Science and Medical Bioscience, School of Advanced Science and Engineering, Waseda University, Tokyo, Japan. ^[9] Department of Molecular Metabolic Regulation, Diabetes Research Center, Research Institute, National Center for Global Health and Medicine, Tokyo, Japan. ^[10] Department of Disease Control, Research Institute, National Center for Global Health and Medicine, Tokyo, Japan. ^[11] Frontier Research Core for Life Science, University of Toyama, Toyama, Japan. ^[12] First Department of Internal Medicine, University of Toyama, Toyama, Japan tobe@med.u-toyama.ac.jp isaousui-tym@umin.ac.jp. ^[13]

主题词 3T3-L1细胞(3T3-L1 Cells);脂肪组织(Adipose Tissue);血管生成素1(Angiopoietin-1);动物(Animals);细胞, 培养的(Cells, Cultured);女(雌)性(Female);成纤维细胞生长因子1(Fibroblast Growth Factor 1);成纤维细胞生长因子10(Fibroblast Growth Factor 10);葡糖耐量试验(Glucose Tolerance Test);缺氧诱导因子1, α亚基(Hypoxia-Inducible Factor 1, alpha Subunit);炎症(Inflammation);胰岛素抗药性(Insulin Resistance);巨噬细胞(Macrophages);男(雄)性(Male);小鼠(Mice);小鼠, 近交C57BL(Mice, Inbred C57BL);小鼠, 基因敲除(Mice, Knockout);髓系细胞(Myeloid Cells);新生血管化, 病理性(Neovascularization, Pathologic);血管内皮生长因子A(Vascular Endothelial Growth Factor A)

DOI 10.2337/db16-0012

PMID 27625023

发布时间 2022-03-10

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HIF-1α in Myeloid Cells Promotes Adipose Tissue Remodeling Toward Insulin Resistance.

Diabetes

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HIF-1α in Myeloid Cells Promotes Adipose Tissue Remodeling Toward Insulin Resistance.

Diabetes

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Diabetes

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