Synthesis and biological evaluation of new 6-hydroxypyridazinone benzisoxazoles: Potential multi-receptor-targeting atypical antipsychotics.
第一作者:
Xudong,Cao
第一单位:
Systems Biology Theme, Department of Biomedical Engineering, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan 430074, China.
作者:
主题词
动物(Animals);抗精神病药(Antipsychotic Agents);结合部位(Binding Sites);药物释放系统(Drug Delivery Systems);药物设计(Drug Design);小鼠(Mice);分子结构(Molecular Structure);硝基咪唑类(Nitroimidazoles);蛋白质结合(Protein Binding);哒嗪类(Pyridazines);大鼠(Rats);受体, 血清素, 5-HT1A(Receptor, Serotonin, 5-HT1A);受体, 血清素, 5-HT2A(Receptor, Serotonin, 5-HT2A)
DOI
10.1016/j.ejmech.2016.09.008
PMID
27639363
发布时间
2017-09-22
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