Dysregulation of neuronal calcium homeostasis in Alzheimer's disease - A therapeutic opportunity?

导出 OA

翻译打印收藏纠错

第一作者： Elena,Popugaeva

第一单位： Laboratory of Molecular Neurodegeneration, Department of Medical Physics, Peter the Great St. Petersburg Polytechnic University, St. Petersburg, Russian Federation. Electronic address: lena.popugaeva@gmail.com.

作者： Elena,Popugaeva ^[1] ; Ekaterina,Pchitskaya ^[2] ; Ilya,Bezprozvanny ^[3]

作者单位： Laboratory of Molecular Neurodegeneration, Department of Medical Physics, Peter the Great St. Petersburg Polytechnic University, St. Petersburg, Russian Federation. Electronic address: lena.popugaeva@gmail.com. ^[1] Laboratory of Molecular Neurodegeneration, Department of Medical Physics, Peter the Great St. Petersburg Polytechnic University, St. Petersburg, Russian Federation. Electronic address: katrincreative@yandex.ru. ^[2] Laboratory of Molecular Neurodegeneration, Department of Medical Physics, Peter the Great St. Petersburg Polytechnic University, St. Petersburg, Russian Federation; Department of Physiology, UT Southwestern Medical Center at Dallas, Dallas, TX, USA. Electronic address: ilya.bezprozvanny@utsouthwestern.edu. ^[3]

关键词 Alzheimer disease Ca(2+) signaling Ca(2+)-calmodulin-dependent kinase II (CaMKII)Calcineurin Mushroom spines Neuronal store-operated Ca(2+) channels Ryanodine receptors Synapse