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Molecular Basis of C-N Bond Cleavage by the Glycyl Radical Enzyme Choline Trimethylamine-Lyase.

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第一作者： Smaranda,Bodea

第一单位： Department of Chemistry and Chemical Biology, Harvard University, 12 Oxford Street, Cambridge, MA 02138, USA.

作者： Smaranda,Bodea ^[1] ; Michael A,Funk ^[2] ; Emily P,Balskus ^[3] ; Catherine L,Drennan ^[4]

作者单位： Department of Chemistry and Chemical Biology, Harvard University, 12 Oxford Street, Cambridge, MA 02138, USA. ^[1] Department of Chemistry, Massachusetts Institute of Technology, 77 Massachusetts, Avenue 68-680, Cambridge, MA 02139, USA. ^[2] Department of Chemistry and Chemical Biology, Harvard University, 12 Oxford Street, Cambridge, MA 02138, USA. Electronic address: balskus@chemistry.harvard.edu. ^[3] Department of Chemistry, Massachusetts Institute of Technology, 77 Massachusetts, Avenue 68-680, Cambridge, MA 02139, USA; Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA; Howard Hughes Medical Institute, Massachusetts Institute of Technology, Cambridge, MA 02139, USA; Center for Environmental Health Sciences, Massachusetts Institute of Technology, Cambridge, MA 02139, USA. Electronic address: cdrennan@mit.edu. ^[4]

医学主题词细菌蛋白质类(Bacterial Proteins);催化域(Catalytic Domain);胆碱(Choline);结晶学, X线(Crystallography, X-Ray);脱硫弧菌属(Desulfovibrio);氢键合(Hydrogen Bonding);裂合酶类(Lyases);甲胺类(Methylamines);模型, 分子(Models, Molecular);蛋白质构象(Protein Conformation);底物特异性(Substrate Specificity)

DOI 10.1016/j.chembiol.2016.07.020

PMID 27642068

发布时间 2018-11-13

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Cell chemical biology

2016年23卷10期

1206-1216页

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Cell chemical biology

2016年23卷10期

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Molecular Basis of C-N Bond Cleavage by the Glycyl Radical Enzyme Choline Trimethylamine-Lyase.

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Molecular Basis of C-N Bond Cleavage by the Glycyl Radical Enzyme Choline Trimethylamine-Lyase.

Cell chemical biology

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Cell chemical biology

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