A Novel Combination of Docosahexaenoic Acid, All-Trans Retinoic Acid, and 1, 25-Dihydroxyvitamin D<sub>3</sub> Reduces T-Bet Gene Expression, Serum Interferon Gamma, and Clinical Scores but Promotes PPARγ Gene Expression in Experimental Autoimmune Encephalomyelitis.

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作者： Mohammad Reza,Shiri-Shahsavar ^[1] ; Abbas,Mirshafiee ^[2] ; Karim,Parastouei ^[3] ; Abbas,Ebrahimi-Kalan ^[4] ; Saeed,Yekaninejad ^[5] ; Farid,Soleymani ^[2] ; Reza,Chahardoli ^[3] ; Ramin,Mazaheri Nezhad Fard ^[6] ; Ali Akbar,Saboor-Yaraghi ^[7]

作者单位： Department of Cellular and Molecular Nutrition, School of Nutritional Sciences and Dietetics, International Campus, Tehran University of Medical Sciences, Tehran, Iran. ^[1] Department of Immunology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran. ^[2] Department of Cellular and Molecular Nutrition, School of Nutritional Sciences and Dietetics, Tehran University of Medical Sciences, Tehran, Iran. ^[3] Neuroscience Department, School of Advanced Medical Sciences, Tabriz University of Medical Sciences, Tabriz, Iran. ^[4] Department of Biostatistics, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran. ^[5] Department of Pathobiology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran. ^[6] Department of Cellular and Molecular Nutrition, School of Nutritional Sciences and Dietetics, International Campus, Tehran University of Medical Sciences, Tehran, Iran. asaboor@tums.ac.ir. ^[7] Department of Immunology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran. asaboor@tums.ac.ir. ^[8]

关键词 ATRA, D3 and DHA combination therapy Experimental autoimmune encephalomyelitis (EAE)Multiple sclerosis (MS)Peroxisome proliferator-activated receptor gamma (PPARγ)T-bet Vitamins