Preclinical and Healthy Volunteer Studies of Potential Drug-Drug Interactions Between Tenapanor and Phosphate Binders.

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作者： Susanne,Johansson ^[1] ; Maria,Leonsson-Zachrisson ^[1] ; Mikael,Knutsson ^[1] ; Andrew G,Spencer ^[2] ; Eric D,Labonté ^[2] ; Desiree,Deshpande ^[2] ; Jill,Kohler ^[3] ; Kenji,Kozuka ^[3] ; Dominique,Charmot ^[2] ; David P,Rosenbaum ^[3]

作者单位： AstraZeneca Gothenburg, Mölndal, Sweden. ^[1] Formerly of Ardelyx Inc., Fremont, CA, USA. ^[2] Ardelyx Inc., Fremont, CA, USA. ^[3]

关键词 chronic kidney disease drug-drug interactions hyperphosphatemia sodium absorption tenapanor

主题词成年人(Adult);动物(Animals);交叉研究(Cross-Over Studies);用药计划表(Drug Administration Schedule);药物评价, 临床前(Drug Evaluation, Preclinical);药物相互作用(Drug Interactions);女(雌)性(Female);人类(Humans);异喹啉类(Isoquinolines);男(雄)性(Male);中年人(Middle Aged);磷(Phosphorus);随机分配(Random Allocation);大鼠(Rats);钠(Sodium);磺胺类(Sulfonamides)

DOI 10.1002/cpdd.307

PMID 27654985

发布时间 2018-12-11

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Clinical pharmacology in drug development

2017年6卷5期

448-456页

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Preclinical and Healthy Volunteer Studies of Potential Drug-Drug Interactions Between Tenapanor and Phosphate Binders.

Clinical pharmacology in drug development

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Clinical pharmacology in drug development

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Preclinical and Healthy Volunteer Studies of Potential Drug-Drug Interactions Between Tenapanor and Phosphate Binders.

Clinical pharmacology in drug development

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Clinical pharmacology in drug development

相关期刊

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