换一批
换一批Discovery and refinement of genetic loci associated with cardiometabolic risk using dense imputation maps.
作者：
Valentina,Iotchkova [1]
;
Jie,Huang [2]
;
John A,Morris [2]
;
Deepti,Jain [3]
;
Caterina,Barbieri [4]
;
Klaudia,Walter [5]
;
Josine L,Min [6]
;
Lu,Chen [2]
;
William,Astle [7]
;
Massimilian,Cocca [2]
;
Patrick,Deelen [8]
;
Heather,Elding [2]
;
Aliki-Eleni,Farmaki [9]
;
Christopher S,Franklin [10]
;
Mattias,Franberg [11]
;
Tom R,Gaunt [12]
;
Albert,Hofman [13]
;
Tao,Jiang [14]
;
Marcus E,Kleber [2]
;
Genevieve,Lachance [15]
;
Jian'an,Luan [2]
;
Giovanni,Malerba [16]
;
Angela,Matchan [8]
;
Daniel,Mead [17]
;
Yasin,Memari [18]
;
Ioanna,Ntalla [10]
;
Kalliope,Panoutsopoulou [19]
;
Raha,Pazoki [20]
;
John R B,Perry [21]
;
Fernando,Rivadeneira [22]
;
Maria,Sabater-Lleal [2]
;
Bengt,Sennblad [2]
;
So-Youn,Shin [2]
;
Lorraine,Southam [23]
;
Michela,Traglia [15]
;
Freerk,van Dijk [2]
;
Elisabeth M,van Leeuwen [17]
;
Gianluigi,Zaza [20]
;
Weihua,Zhang [21]
;
UK10K Consortium [17]
;
Najaf,Amin [24]
;
Adam,Butterworth [16]
;
John C,Chambers [16]
;
George,Dedoussis [2]
;
Abbas,Dehghan [8]
;
Oscar H,Franco [2]
;
Lude,Franke [25]
;
Mattia,Frontini [7]
;
Giovanni,Gambaro [13]
;
Paolo,Gasparini [14]
;
Anders,Hamsten [17]
;
Aaron,Issacs [26]
;
Jaspal S,Kooner [27]
;
Charles,Kooperberg [17]
;
Claudia,Langenberg [10]
;
Winfried,Marz [28]
;
Robert A,Scott [27]
;
Morris A,Swertz [15]
;
Daniela,Toniolo [17]
;
Andre G,Uitterlinden [17]
;
Cornelia M,van Duijn [14]
;
Hugh,Watkins [29]
;
Eleftheria,Zeggini [30]
;
Mathew T,Maurano [11]
;
Nicholas J,Timpson [12]
;
Alexander P,Reiner [31]
;
Paul L,Auer [16]
;
Nicole,Soranzo [17]
作者单位：
European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK.
[1]
Human Genetics, Wellcome Trust Sanger Institute, Hinxton, Cambridge, UK.
[2]
Boston VA Research Institute, Boston, Massachusetts, USA.
[3]
Centre for Clinical Epidemiology, Lady Davis Institute for Medical Research, Jewish General Hospital, McGill University, Montréal, Québec, Canada.
[4]
Department of Human Genetics, McGill University, Montréal, Québec, Canada.
[5]
Department of Biostatistics, University of Washington, Seattle, Washington, USA.
[6]
Division of Genetics and Cell Biology, San Raffaele Scientific Institute, Milan, Italy.
[7]
MRC Integrative Epidemiology Unit, School of Social and Community Medicine, University of Bristol, Bristol, UK.
[8]
Department of Hematology, University of Cambridge, Cambridge, UK.
[9]
Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.
[10]
Medical Genetics, Institute for Maternal and Child Health IRCCS "Burlo Garofolo", Trieste, Italy.
[11]
Department of Medical, Surgical and Health Sciences, University of Trieste, Trieste, Italy.
[12]
University of Groningen, University Medical Center Groningen, Genomics Coordination Center, Groningen, Netherlands.
[13]
University of Groningen, University Medical Center Groningen, Department of Genetics, Groningen, Netherlands.
[14]
Department of Nutrition and Dietetics, School of Health Science and Education, Harokopio University, Athens, Greece.
[15]
Cardiovascular Medicine Unit, Dep. Medicine, Karolinska Institute, Stockholm, Sweden.
[16]
Department of Epidemiology, Erasmus University Medical Center, Rotterdam, Netherlands.
[17]
Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA.
[18]
Vth Department of Medicine, Medical Faculty, Mannheim, Germany.
[19]
Department of Twin Research & Genetic Epidemiology, King's College London, Londo, UK.
[20]
MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge Biomedical Campus, Cambridge, UK.
[21]
Biology and Genetics, Department Neurosciences, Biomedicine and Movement Sciences, University of Verona, Verona, Italy.
[22]
William Harvey Research Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, UK.
[23]
Department of Internal Medicine, Erasmus University Medical Center, Rotterdam, Netherlands.
[24]
Wellcome Trust Centre for Human Genetics, Roosevelt Drive, Oxford, UK.
[25]
Renal Unit, Department of Medicine, University of Verona, Verona, Italy.
[26]
Department of Epidemiology and Biostatistics, Imperial College London, St Mary's campus, London, UK.
[27]
The National Institute for Health Research Blood and Transplant Unit (NIHR BTRU) in Donor Health and Genomics at the University of Cambridge, University of Cambridge, Cambridge, UK.
[28]
University of Cambridge, Cambridge, UK.
[29]
Division of Nephrology and Dialysis, Institute of Internal Medicine, Renal Program, Columbus-Gemelli University Hospital, Catholic University, Rome, Italy.
[30]
Experimental Genetics Division, Sidra, Doha, Qatar.
[31]
National Heart and Lung Institute, Imperial College London, London, UK.
[32]
Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA.
[33]
Clinical Institute of Medical and Chemical Laboratory Diagnostics, Medical University of Graz, Graz, Austria.
[34]
Synlab Academy, Synlab Holding Deutschland GmbH, Mannheim, Germany.
[35]
Medical Clinic V (Nephrology, Hypertensiology, Rheumatology, Endocrinolgy, Diabetology), Mannheim Medical Faculty, Heidelberg University, Mannheim, Germany.
[36]
LifeLines Cohort Study, University Medical Center Groningen, Groningen, Netherlands.
[37]
Radcliffe Department of Medicine, University of Oxford, John Radcliffe Hospital, Oxford, UK.
[38]
Institute for Systems Genetics, New York University Langone Medical Center, New York, USA.
[39]
Department of Epidemiology, University of Washington, Seattle, Washington, USA.
[40]
Zilber School of Public Health, University of Wisconsin-Milwaukee, Milwaukee, Wisconsin, USA.
[41]
主题词
女(雌)性(Female);基因座(Genetic Loci);疾病遗传易感性(Genetic Predisposition to Disease);遗传变异(Genetic Variation);基因组, 人(Genome, Human);全基因组关联研究(Genome-Wide Association Study);心脏病(Heart Diseases);血液病(Hematologic Diseases);人类(Humans);男(雄)性(Male);数量性状基因座位(Quantitative Trait Loci);序列分析, DNA(Sequence Analysis, DNA)
DOI
10.1038/ng.3668
PMID
27668658
发布时间
2024-06-10
- 浏览30
Nature genetics
Nature genetics
1303-1312页
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