Epigenetic Variability of CD4+CD25+ Tregs Contributes to the Pathogenesis of Autoimmune Diseases.

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第一作者： Ye,Shu

第一单位： Department of Dermatology, The Second Xiangya Hospital, Central South University, Hunan Key Laboratory of Medical Epigenetics, Changsha, China.;Department of Dermatology, Hunan Province Children's Hospital, Changsha, China.

作者： Ye,Shu ^[1] ; Qinghua,Hu ^[2] ; Hai,Long ^[3] ; Christopher,Chang ^[4] ; Qianjin,Lu ^[3] ; Rong,Xiao ^[5]

作者单位： Department of Dermatology, The Second Xiangya Hospital, Central South University, Hunan Key Laboratory of Medical Epigenetics, Changsha, China.;Department of Dermatology, Hunan Province Children's Hospital, Changsha, China. ^[1] Department of Cardiovascular Surgery, Xiangya Hospital, Central South University, Changsha, China. ^[2] Department of Dermatology, The Second Xiangya Hospital, Central South University, Hunan Key Laboratory of Medical Epigenetics, Changsha, China. ^[3] Division of Rheumatology, Allergy and Clinical Immunology, University of California at Davis, Davis, CA, USA. ^[4] Department of Dermatology, The Second Xiangya Hospital, Central South University, Hunan Key Laboratory of Medical Epigenetics, Changsha, China. xiaorong65@aliyun.com. ^[5]

关键词 Autoimmune diseases DNA methylation Epigenetic mechanism Foxp3 Histone deacetylation MicroRNA Tregs

主题词自身免疫疾病(Autoimmune Diseases);后成说, 遗传(Epigenesis, Genetic);基因表达调控(Gene Expression Regulation);人类(Humans);T淋巴细胞, 调节性(T-Lymphocytes, Regulatory)

DOI 10.1007/s12016-016-8590-3

PMID 27687891

发布时间 2018-11-13

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