Modeling Fragile X Syndrome Using Human Pluripotent Stem Cells.

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作者： Hagar,Mor-Shaked ^[1] ; Rachel,Eiges ^[2]

作者单位： Stem Cell Research Laboratory, Medical Genetics Institute, Shaare Zedek Medical Center Affiliated with the Hebrew University School of Medicine, Jerusalem 91031, Israel. hagar.mor@mail.huji.ac.il. ^[1] Stem Cell Research Laboratory, Medical Genetics Institute, Shaare Zedek Medical Center Affiliated with the Hebrew University School of Medicine, Jerusalem 91031, Israel. rachela@szmc.org.il. ^[2]

关键词 FMR1 gene FMRP disease modeling epigenetics fragile X syndrome human embryonic stem cells neurodevelopment patient-derived iPS cells repeat somatic instability

DOI 10.3390/genes7100077

PMID 27690107

发布时间 2019-11-20

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