Selective amotivation deficits following chronic psychosocial stress in mice.

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作者： Alejandro,Tsai Cabal ^[1] ; Horea-Ioan,Ioanas ^[2] ; Erich,Seifritz ^[3] ; Bechara J,Saab ^[4]

作者单位： Preclinical Laboratory for Translational Research into Affective Disorders, DPPP, Psychiatric Hospital, University of Zurich, August-Forel-Strasse 7, CH-8008, Zurich, Switzerland; Neuroscience Center Zurich, University of Zurich and ETH, Zurich, Switzerland; Department of Biology, ETH, Zurich, Switzerland. ^[1] Preclinical Laboratory for Translational Research into Affective Disorders, DPPP, Psychiatric Hospital, University of Zurich, August-Forel-Strasse 7, CH-8008, Zurich, Switzerland; Neuroscience Center Zurich, University of Zurich and ETH, Zurich, Switzerland; Institute for Biomedical Engineering, University and ETH Zurich, CH-8093, Zurich, Switzerland. ^[2] Preclinical Laboratory for Translational Research into Affective Disorders, DPPP, Psychiatric Hospital, University of Zurich, August-Forel-Strasse 7, CH-8008, Zurich, Switzerland; Neuroscience Center Zurich, University of Zurich and ETH, Zurich, Switzerland; Department of Psychiatry, Psychotherapy and Pesychosomatics (DPPP), Psychiatric Hospital, University of Zurich, Lengstrasse 31, CH-8032, Zurich, Switzerland. ^[3] Preclinical Laboratory for Translational Research into Affective Disorders, DPPP, Psychiatric Hospital, University of Zurich, August-Forel-Strasse 7, CH-8008, Zurich, Switzerland; Neuroscience Center Zurich, University of Zurich and ETH, Zurich, Switzerland; Department of Psychiatry, Psychotherapy and Pesychosomatics (DPPP), Psychiatric Hospital, University of Zurich, Lengstrasse 31, CH-8032, Zurich, Switzerland. Electronic address: bechara.saab@uzh.ch. ^[4]

关键词 Curiosity Exploration Major depressive disorder (MDD)Mice New frontier task (NFT)Spatial memory