Pharmacogenetics of neurological and psychiatric diseases at older age: has the time come?

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第一作者： Madia,Lozupone

第一单位： a Unit of Neurodegenerative Disease, Department of Basic Medicine Sciences, Neuroscience, and Sense Organs , University of Bari 'Aldo Moro,' , Bari , Italy.

作者： Madia,Lozupone ^[1] ; Francesco,Panza ^[1] ; Eleonora,Stella ^[2] ; Maddalena,La Montagna ^[3] ; Paola,Bisceglia ^[4] ; Giuseppe,Miscio ^[4] ; Ilaria,Galizia ^[3] ; Antonio,Daniele ^[5] ; Lazzaro,di Mauro ^[4] ; Antonello,Bellomo ^[6] ; Giancarlo,Logroscino ^[5] ; Antonio,Greco ^[4] ; Davide,Seripa ^[1]

作者单位： a Unit of Neurodegenerative Disease, Department of Basic Medicine Sciences, Neuroscience, and Sense Organs , University of Bari 'Aldo Moro,' , Bari , Italy. ^[1] b Unit of Neurodegenerative Disease, Department of Clinical Research in Neurology , University of Bari 'Aldo Moro' at 'Pia Fondazione Card. G. Panico,' , Tricase , Lecce , Italy. ^[2] c Geriatric Unit and Gerontology-Geriatrics Research Laboratory, Department of Medical Sciences , IRCCS Casa Sollievo della Sofferenza , San Giovanni Rotondo , Italy. ^[3] d Psychiatric Unit, Department of Clinical and Experimental Medicine , University of Foggia , Foggia , Italy. ^[4] e Laboratory of Clinical Chemistry, Department of Clinical Pathology , IRCCS Casa Sollievo della Sofferenza , San Giovanni Rotondo , Italy. ^[5] f Institute of Neurology , Catholic University of Sacred Heart , Rome , Italy. ^[6]

关键词 5-HTT 5-hydroxytriptamine transporter CYP2D6 DAT Therapeutic failure adverse drug reaction cytochrome P450 dopamine transporter pharmacogenetics psychiatric disorders