Endophilin-A Deficiency Induces the Foxo3a-Fbxo32 Network in the Brain and Causes Dysregulation of Autophagy and the Ubiquitin-Proteasome System.-论文-万方医学网

作者： John D,Murdoch ^[1] ; Christine M,Rostosky ^[2] ; Sindhuja,Gowrisankaran ^[2] ; Amandeep S,Arora ^[2] ; Sandra-Fausia,Soukup ^[3] ; Ramon,Vidal ^[4] ; Vincenzo,Capece ^[4] ; Siona,Freytag ^[2] ; Andre,Fischer ^[5] ; Patrik,Verstreken ^[3] ; Stefan,Bonn ^[4] ; Nuno,Raimundo ^[6] ; Ira,Milosevic ^[7]

作者单位： European Neuroscience Institute (ENI), 37077 Göttingen, Germany; Institute of Cellular Biochemistry, University Medical Center Göttingen (UMG), 37073 Göttingen, Germany. ^[1] European Neuroscience Institute (ENI), 37077 Göttingen, Germany. ^[2] VIB Center for Brain & Disease Research, 3000 Leuven, Belgium; KU Leuven Department of Human Genetics, Leuven Institute for Neurodegenerative Disease (LIND), 3000 Leuven, Belgium. ^[3] Computational Systems Biology, German Center for Neurodegenerative Diseases (DZNE), 37077 Göttingen, Germany. ^[4] Epigenetics and Systems Medicine in Neurodegenerative Diseases, German Center for Neurodegenerative Diseases (DZNE), 37077 Göttingen, Germany; Department of Psychiatry and Psychotherapy, University Medical Center Göttingen, 37077 Göttingen, Germany. ^[5] Institute of Cellular Biochemistry, University Medical Center Göttingen (UMG), 37073 Göttingen, Germany. Electronic address: nuno.raimundo@med.uni-goettingen.de. ^[6] European Neuroscience Institute (ENI), 37077 Göttingen, Germany. Electronic address: imilose@gwdg.de. ^[7]

主题词酰基转移酶类(Acyltransferases);衰老(Aging);动物(Animals);细胞凋亡(Apoptosis);共济失调(Ataxia);自噬(Autophagy);脑(Brain);海马(Hippocampus);内环境稳定(Homeostasis);人类(Humans);男(雄)性(Male);小鼠(Mice);小鼠, 基因敲除(Mice, Knockout);动作障碍(Movement Disorders);肌蛋白质类(Muscle Proteins);突变(Mutation);神经变性(Nerve Degeneration);帕金森病(Parkinson Disease);蛋白酶体内肽酶复合物(Proteasome Endopeptidase Complex);蛋白质结合(Protein Binding);SKP Cullin F-框蛋白质连接酶类(SKP Cullin F-Box Protein Ligases);转录, 遗传(Transcription, Genetic);泛素(Ubiquitin);增量调节(Up-Regulation)

DOI 10.1016/j.celrep.2016.09.058

PMID 27720640

发布时间 2022-01-29

检索历史清除

Endophilin-A Deficiency Induces the Foxo3a-Fbxo32 Network in the Brain and Causes Dysregulation of Autophagy and the Ubiquitin-Proteasome System.

Cell reports

相似文献

Cell reports

相关期刊

参考文献：
指定格式：	NoteExpress EndNote RefWorks NoteFirst

检索历史 清除

Endophilin-A Deficiency Induces the Foxo3a-Fbxo32 Network in the Brain and Causes Dysregulation of Autophagy and the Ubiquitin-Proteasome System.

Cell reports

相似文献

Cell reports

相关期刊

检索历史清除