Identification of non-reported bupropion metabolites in human plasma.

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作者： Jamie N,Connarn ^[1] ; Ruijuan,Luo ^[1] ; Jim,Windak ^[2] ; Xinyuan,Zhang ^[3] ; Andrew,Babiskin ^[3] ; Marisa,Kelly ^[4] ; Gloria,Harrington ^[4] ; Vicki L,Ellingrod ^[5] ; Masoud,Kamali ^[4] ; Melvin,McInnis ^[4] ; Duxin,Sun ^[1]

作者单位： Department of Pharmaceutical Sciences University of Michigan, Ann Arbor, MI, 48109, USA. ^[1] Department of Chemistry, University of Michigan, Ann Arbor, MI, 48109, USA. ^[2] Division of Quantitative Methods and Modeling, Office of Research and Standards, Office of Generic Drugs, Center for Drug Evaluation and Research, US Food and Drug Administration, Silver Spring, Maryland, 20993, USA. ^[3] Department of Psychiatry, University of Michigan Medical School, Ann Arbor, 48109, USA. ^[4] Department of Clinical Pharmacy, University of Michigan, Ann Arbor, MI, 48109, USA. ^[5]

关键词 LC-MS/MS bupropion metabolite identification

主题词抗抑郁药, 第二代(Antidepressive Agents, Second-Generation);安非他酮(Bupropion);色谱法, 液相(Chromatography, Liquid);人类(Humans);光谱法, 质量, 电喷雾电离(Spectrometry, Mass, Electrospray Ionization)

DOI 10.1002/bdd.2046

PMID 27723114

发布时间 2021-01-09

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准确一般字义偏差语意偏离译文作用小提交