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Distinct Functions of Senescence-Associated Immune Responses in Liver Tumor Surveillance and Tumor Progression.

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第一作者： Tobias,Eggert

第一单位： Gastrointestinal Malignancy Section, Thoracic and Gastrointestinal Oncology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA.

作者： Tobias,Eggert ^[1] ; Katharina,Wolter ^[2] ; Juling,Ji ^[3] ; Chi,Ma ^[1] ; Tetyana,Yevsa ^[2] ; Sabrina,Klotz ^[2] ; José,Medina-Echeverz ^[1] ; Thomas,Longerich ^[4] ; Marshonna,Forgues ^[3] ; Florian,Reisinger ^[5] ; Mathias,Heikenwalder ^[5] ; Xin Wei,Wang ^[3] ; Lars,Zender ^[6] ; Tim F,Greten ^[7]

作者单位： Gastrointestinal Malignancy Section, Thoracic and Gastrointestinal Oncology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA. ^[1] Division of Gastrointestinal Oncology, Department of Internal Medicine I, University of Tübingen, 72076 Tübingen, Germany. ^[2] Laboratory of Human Carcinogenesis, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA. ^[3] Institute of Pathology, University Hospital RWTH Aachen, 52074 Aachen, Germany. ^[4] Institute of Virology, Technische Universität München and Helmholtz Zentrum München, 81675 Munich, Germany; Division of Chronic Inflammation and Cancer, German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany. ^[5] Division of Gastrointestinal Oncology, Department of Internal Medicine I, University of Tübingen, 72076 Tübingen, Germany; Translational Gastrointestinal Oncology Group within the German Consortium for Translational Cancer Research (DKTK), German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany. Electronic address: lars.zender@med.uni-tuebingen.de. ^[6] Gastrointestinal Malignancy Section, Thoracic and Gastrointestinal Oncology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA. Electronic address: tim.greten@nih.gov. ^[7]

关键词 CCL2 CCR2 HCC MDSC NK cells hepatocellular carcinoma liver cancer macrophages myeloid cells senescence