Cell-Based High-Throughput Screening Assay Identifies 2',2'-Difluoro-2'-deoxycytidine Gemcitabine as a Potential Antipoliovirus Agent.

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作者： Zhuoran,Zhang ^[1] ; Enzhuo,Yang ^[1] ; Chunmiao,Hu ^[2] ; Han,Cheng ^[1] ; Crystal Y,Chen ^[1] ; Dan,Huang ^[1] ; Richard,Wang ^[1] ; Yue,Zhao ^[1] ; Lijun,Rong ^[1] ; Marco,Vignuzzi ^[1] ; Hongbo,Shen ^[3] ; Ling,Shen ^[2] ; Zheng W,Chen ^[1]

作者单位： Department of Microbiology and Immunology and Center for Primate Biomedical Research, University of Illinois College of Medicine , 909 South Wolcott Avenue, E704, M/C790, Chicago, Illinois 60612, United States. ^[1] Unit of anti-tuberculosis immunity, CAS Key Laboratory of Molecular Virology and Immunology, Institut Pasteur of Shanghai, Chinese Academy of Sciences , Shanghai 200031, China. ^[2] Viral Populations and Pathogenesis Unit, CNRS UMR 3569, Institut Pasteur , 25-28 rue du Dr. Roux, 75724 Paris cedex 15, France. ^[3] Institut Pasteur of Shanghai, Shanghai 200031, China. ^[4]

关键词 RNA-dependent RNA polymerase inhibitor antiviral gemcitabine poliovirus

主题词抗病毒药(Antiviral Agents);脱氧胞苷(Deoxycytidine);高通量筛选分析(High-Throughput Screening Assays);人类(Humans);脊髓灰质炎病毒(Poliovirus);病毒复制(Virus Replication)

DOI 10.1021/acsinfecdis.6b00116

PMID 27733043

发布时间 2022-12-07

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ACS infectious diseases

2017年3卷1期

45-53页

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Cell-Based High-Throughput Screening Assay Identifies 2',2'-Difluoro-2'-deoxycytidine Gemcitabine as a Potential Antipoliovirus Agent.

ACS infectious diseases

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ACS infectious diseases

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Cell-Based High-Throughput Screening Assay Identifies 2',2'-Difluoro-2'-deoxycytidine Gemcitabine as a Potential Antipoliovirus Agent.

ACS infectious diseases

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ACS infectious diseases

相关期刊

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