Oligomeric interface modulation causes misregulation of purine 5´-nucleotidase in relapsed leukemia.

导出 OA

翻译打印收藏纠错

第一作者： Aleš,Hnízda

第一单位： Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, Flemingovo nam. 2, Prague 6, 166 10, Czech Republic. hnizda@uochb.cas.cz.

作者： Aleš,Hnízda ^[1] ; Jana,Škerlová ^[2] ; Milan,Fábry ^[3] ; Petr,Pachl ^[2] ; Martina,Šinalová ^[2] ; Lukáš,Vrzal ^[2] ; Petr,Man ^[4] ; Petr,Novák ^[4] ; Pavlína,Řezáčová ^[2] ; Václav,Veverka ^[3]

作者单位： Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, Flemingovo nam. 2, Prague 6, 166 10, Czech Republic. hnizda@uochb.cas.cz. ^[1] Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, Flemingovo nam. 2, Prague 6, 166 10, Czech Republic. ^[2] Institute of Molecular Genetics, Academy of Sciences of the Czech Republic, Videnska 1083, Prague 4, 142 20, Czech Republic. ^[3] Institute of Microbiology, Academy of Sciences of the Czech Republic, Videnska 1083, Prague 4, 142 20, Czech Republic. ^[4] Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, Flemingovo nam. 2, Prague 6, 166 10, Czech Republic. veverka@uochb.cas.cz. ^[5]

关键词 Allosteric regulation Cancer mutations Nucleotidase Purine metabolism Relapsed ALL