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首页> The Journal of biological chemistry> A New Splice Variant of Large Conductance Ca2+-activated K+ (BK) Channel α Subunit Alters Human Chondrocyte Function.

A New Splice Variant of Large Conductance Ca2+-activated K+ (BK) Channel α Subunit Alters Human Chondrocyte Function.

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作者： Yoshiaki,Suzuki ^[1] ; Susumu,Ohya ^[1] ; Hisao,Yamamura ^[2] ; Wayne R,Giles ^[1] ; Yuji,Imaizumi ^[3]

作者单位： From the Department of Molecular and Cellular Pharmacology, Graduate School of Pharmaceutical Sciences, Nagoya City University, 3-1 Tanabedori, Mizuhoku, Nagoya 467-8603, Japan. ^[1] the Department of Pharmacology, Division of Pathological Sciences, Kyoto Pharmaceutical University, Kyoto 607-8414, Japan, and. ^[2] the Faculties of Kinesiology and Medicine, University of Calgary, Calgary, Alberta T2N 1N4, Canada. ^[3] From the Department of Molecular and Cellular Pharmacology, Graduate School of Pharmaceutical Sciences, Nagoya City University, 3-1 Tanabedori, Mizuhoku, Nagoya 467-8603, Japan, yimaizum@phar.nagoya-cu.ac.jp. ^[4]

关键词 alternative splicing chondrocyte fluorescence resonance energy transfer (FRET)molecular imaging patch clamp potassium channel single molecule biophysics

主题词选择性剪接(Alternative Splicing);动物(Animals);软骨细胞(Chondrocytes);HEK293细胞(HEK293 Cells);人类(Humans);大电导钙激活钾通道α亚基(Large-Conductance Calcium-Activated Potassium Channel alpha Subunits);小鼠(Mice);诱变, 定点(Mutagenesis, Site-Directed);骨关节炎(Osteoarthritis)

DOI 10.1074/jbc.M116.743302

PMID 27758860

发布时间 2021-02-09

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The Journal of biological chemistry

The Journal of biological chemistry

2016年291卷46期

24247-24260页

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