换一批
第一作者：
Johanna,Jakobsdottir
第一单位：
Icelandic Heart Association, Kopavogur, Iceland.
作者：
Johanna,Jakobsdottir [1]
;
Sven J,van der Lee [2]
;
Joshua C,Bis [3]
;
Vincent,Chouraki [4]
;
David,Li-Kroeger [5]
;
Shinya,Yamamoto [6]
;
Megan L,Grove [7]
;
Adam,Naj [8]
;
Maria,Vronskaya [9]
;
Jose L,Salazar [10]
;
Anita L,DeStefano [11]
;
Jennifer A,Brody [3]
;
Albert V,Smith [12]
;
Najaf,Amin [2]
;
Rebecca,Sims [9]
;
Carla A,Ibrahim-Verbaas [13]
;
Seung-Hoan,Choi [11]
;
Claudia L,Satizabal [4]
;
Oscar L,Lopez [14]
;
Alexa,Beiser [15]
;
M Arfan,Ikram [16]
;
Melissa E,Garcia [17]
;
Caroline,Hayward [18]
;
Tibor V,Varga [19]
;
Samuli,Ripatti [20]
;
Paul W,Franks [21]
;
Göran,Hallmans [22]
;
Olov,Rolandsson [23]
;
Jan-Håkon,Jansson [24]
;
David J,Porteous [25]
;
Veikko,Salomaa [26]
;
Gudny,Eiriksdottir [1]
;
Kenneth M,Rice [27]
;
Hugo J,Bellen [28]
;
Daniel,Levy [29]
;
Andre G,Uitterlinden [30]
;
Valur,Emilsson [31]
;
Jerome I,Rotter [32]
;
Thor,Aspelund [33]
;
Cohorts for Heart and Aging Research in Genomic Epidemiology consortium [34]
;
Alzheimer’s Disease Genetic Consortium [35]
;
Genetic and Environmental Risk in Alzheimer’s Disease consortium [17]
;
Christopher J,O'Donnell [2]
;
Annette L,Fitzpatrick [36]
;
Lenore J,Launer [9]
;
Albert,Hofman [36]
;
Li-San,Wang [37]
;
Julie,Williams [38]
;
Gerard D,Schellenberg [4]
;
Eric,Boerwinkle [6]
;
Bruce M,Psaty [12]
;
Sudha,Seshadri [2]
;
Joshua M,Shulman ;
Vilmundur,Gudnason ;
Cornelia M,van Duijn
作者单位：
Icelandic Heart Association, Kopavogur, Iceland.
[1]
Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands.
[2]
Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, Washington, United States of America.
[3]
Boston University School of Medicine, Boston, Massachusetts, United States of America.;Framingham Heart Study, Framingham, Massachusetts, United States of America.
[4]
Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas, United States of America.;Jan and Dan Duncan Neurological Research Institute, Texas Children's Hospital Houston, Texas, United States of America.
[5]
Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas, United States of America.;Jan and Dan Duncan Neurological Research Institute, Texas Children's Hospital Houston, Texas, United States of America.;Program in Developmental Biology, Baylor College of Medicine, Houston, Texas, United States of America.
[6]
School of Public Health, Human Genetics Center, The University of Texas Health Science Center at Houston, Houston, Texas, United States of America.
[7]
Department of Biostatistics and Epidemiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America.
[8]
Institute of Psychological Medicine and Clinical Neurosciences, Medical Research Council (MRC) Centre for Neuropsychiatric Genetics & Genomics, Cardiff University, Cardiff, United Kingdom.
[9]
Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas, United States of America.
[10]
Framingham Heart Study, Framingham, Massachusetts, United States of America.;Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts, United States of America.
[11]
Icelandic Heart Association, Kopavogur, Iceland.;Faculty of Medicine, University of Iceland, Reykjavik, Iceland, United States of America.
[12]
Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands.;Department of Neurology, Erasmus University Medical Center, CA Rotterdam, The Netherlands.
[13]
Department of Neurology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, United States of America.
[14]
Boston University School of Medicine, Boston, Massachusetts, United States of America.;Framingham Heart Study, Framingham, Massachusetts, United States of America.;Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts, United States of America.
[15]
Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands.;Department of Neurology, Erasmus University Medical Center, CA Rotterdam, The Netherlands.;Departments of Radiology, Erasmus University Medical Center, CA Rotterdam, The Netherlands.
[16]
Laboratory of Epidemiology and Population Sciences, National Institute on Aging, Bethesda, Maryland, United States of America.
[17]
MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, United Kingdom.;Generation Scotland, Centre for Genomic and Experimental Medicine, University of Edinburgh, Edinburgh, United Kingdom.
[18]
Department of Clinical Sciences, Genetic and Molecular Epidemiology Unit, Lund University, Malmö, Sweden.
[19]
Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland.;Department of Public Health, University of Helsinki, Helsinki, Finland.
[20]
Department of Clinical Sciences, Genetic and Molecular Epidemiology Unit, Lund University, Malmö, Sweden.;Department of Public Health & Clinical Medicine, Umeå University Hospital, Umeå, Sweden.;Department of Nutrition, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, United States of America.
[21]
Department of Biobank Research, Umeå University, Umeå, Sweden.
[22]
Department of Public Health & Clinical Medicine, Section for Family Medicine, Umeå University, Umeå, Sweden.
[23]
Department of Public Health & Clinical Medicine, Umeå University Hospital, Umeå, Sweden.;Research Unit, Skellefteå Hospital, Skellefteå, Sweden.
[24]
Generation Scotland, Centre for Genomic and Experimental Medicine, University of Edinburgh, Edinburgh, United Kingdom.;Centre for Genomic and Experimental Medicine, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, United Kingdom.
[25]
National Institute for Health and Welfare, Helsinki, Finland.
[26]
Department of Biostatistics, University of Washington, Seattle, Washington, United States of America.
[27]
Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas, United States of America.;Jan and Dan Duncan Neurological Research Institute, Texas Children's Hospital Houston, Texas, United States of America.;Program in Developmental Biology, Baylor College of Medicine, Houston, Texas, United States of America.;Howard Hughes Medical Institute, Durham, North Carolina, United States of America.
[28]
Framingham Heart Study, Framingham, Massachusetts, United States of America.;Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland, United states of America.;Boston University School of Medicine, Boston, Massachusetts, United States of America.
[29]
Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands.;Department of Internal Medicine, Erasmus University Medical Center, CA Rotterdam, The Netherlands.
[30]
Icelandic Heart Association, Kopavogur, Iceland.;Faculty of Pharmaceutical Sciences, University of Iceland, Reykjavik, Iceland.
[31]
Institute for Translational Genomics and Population Sciences, Los Angeles BioMedical Research Institute and Departments of Medicine and Pediatrics, Harbor-UCLA Medical Center, Torrance, California, United States of America.
[32]
Icelandic Heart Association, Kopavogur, Iceland.;Centre for Public Health, University of Iceland, Reykjavik, Iceland.
[33]
Framingham Heart Study, Framingham, Massachusetts, United States of America.;Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland, United states of America.
[34]
Department of Epidemiology, University of Washington, Seattle, Washington, United States of America.;Collaborative Health Studies Coordinating Center, Seattle, Washington, United States of America.
[35]
Department of Pathology and Laboratory of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America.
[36]
School of Public Health, Human Genetics Center, The University of Texas Health Science Center at Houston, Houston, Texas, United States of America.;Human Genome Sequencing Center, Baylor College of Medicine, Houston, Texas, United States of America.
[37]
Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, Washington, United States of America.;Department of Epidemiology, University of Washington, Seattle, Washington, United States of America.;Department of Health Services, University of Washington, Seattle, Washington, United States of America.;Group Health Research Institute, Group Health Cooperative, Seattle, Washington, United States of America.
[38]
主题词
发病年龄(Age of Onset);老年人(Aged);等位基因(Alleles);阿尔茨海默病(Alzheimer Disease);淀粉样β蛋白前体(Amyloid beta-Protein Precursor);动物(Animals);载脂蛋白E类(Apolipoproteins E);果蝇蛋白质类(Drosophila Proteins);黑腹果蝇(Drosophila melanogaster);女(雌)性(Female);全基因组关联研究(Genome-Wide Association Study);基因组学(Genomics);人类(Humans);冰岛(Iceland);细胞内信号肽和蛋白质类(Intracellular Signaling Peptides and Proteins);男(雄)性(Male);膜蛋白质类(Membrane Proteins);突变(Mutation);表型(Phenotype);受体, Notch(Receptors, Notch);原肌球蛋白(Tropomyosin)
DOI
10.1371/journal.pgen.1006327
PMID
27764101
发布时间
2025-05-30
- 浏览13
PLoS genetics
PLoS genetics
e1006327页
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