首页> International journal of pharmaceutics> Trospium chloride is absorbed from two intestinal "absorption windows" with different permeability in healthy subjects.

Trospium chloride is absorbed from two intestinal "absorption windows" with different permeability in healthy subjects.

导出原文传递

翻译打印收藏纠错

第一作者： Tobias,Tadken

第一单位： Department of Clinical Pharmacology, Center of Drug Absorption and Transport, University Medicine of Greifswald, Greifswald, Germany.

作者： Tobias,Tadken ^[1] ; Michael,Weiss ^[2] ; Christiane,Modess ^[1] ; Danilo,Wegner ^[1] ; Tarek,Roustom ^[1] ; Claudia,Neumeister ^[3] ; Ulrich,Schwantes ^[3] ; Hans-Ulrich,Schulz ^[4] ; Werner,Weitschies ^[5] ; Werner,Siegmund ^[6]

作者单位： Department of Clinical Pharmacology, Center of Drug Absorption and Transport, University Medicine of Greifswald, Greifswald, Germany. ^[1] Department of Pharmacology, Martin Luther University Halle-Wittenberg, Germany. ^[2] Department Medical Science/Clinical Research, Dr. R. Pfleger GmbH, Bamberg, Germany. ^[3] Laboratory for Contract Research in Clinical Pharmacology and Biopharmaceutical Analytics, Bad Schwartau, Germany. ^[4] Department of Pharmaceutical Technology and Biopharmaceutics, Center of Drug Absorption and Transport, University of Greifswald, Greifswald, Germany. ^[5] Department of Clinical Pharmacology, Center of Drug Absorption and Transport, University Medicine of Greifswald, Greifswald, Germany. Electronic address: werner.siegmund@uni-greifswald.de. ^[6]

关键词 Food effects Gastric infusion OCT1 P-glycoprotein Pharmacokinetics Trospium chloride